Supplement
Adaptogenic root extract with possible androgen-axis effects.[3298,3918,4565, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
37/100
Early depth from human/RCT/meta counts
Community Direction
24
Positive Lean • confidence Low
Safety Friction
71/100
Moderate signal from adverse/interaction markers
Data Completeness
100%
Studies 5 • mentions 14 • links 16
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Goal alignment: Hormone Health, Energy, Performance.[61,272,366, etc.]
Dose guide: Human-study daily dose: 200 mg/day (early-confidence extraction from PubMed abstracts)..[61,272,366, etc.]
Category
Botanical
Evidence Tier
MEDIUM
Daily Guide
Human-study daily dose: 200 mg/day (early-confidence extraction from PubMed abstracts).
Dosing Guide
Human-study daily dose: 200 mg/day (early-confidence extraction from PubMed abstracts).[3298,, etc.]
Clinical Depth
Humans: 8 • RCTs: 1 • Meta: 0
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 12 • Interactions: 3
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
24 total studies
Timeline
Total indexed
24
Animal-only studies
15
Safety adverse signals
12
In vitro / tissue
10
Human studies
8
Interaction signals
3
Weighted direction score: 24 (Positive Lean)
Medium when human evidence exists but is limited, or when animal evidence volume is substantial.
Total indexed
24
Animal-only studies
15
Safety adverse signals
12
In vitro / tissue
10
Human studies
8
Interaction signals
3
Randomized trials
1
Meta-analyses
0
Distribution of evidence by study design strength
Evidence Strength: Early
Composite of study volume, RCTs, and meta-analyses
PMID 33541567 • 2021 Mar
A 6-month, double-blind, placebo-controlled, randomized trial to evaluate the effect of Eurycoma longifolia (Tongkat Ali) and concurrent training on erectile function and testosterone levels in androgen deficiency of aging males (ADAM).
Maturitas
Open PubMedPMID 36013514 • 2022 Aug 4
Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A Systematic Review and Meta-Analysis of Clinical Trials.
Medicina (Kaunas)
Open PubMedPMID 31036522 • 2019 Jun
An Analysis of Popular Online Erectile Dysfunction Supplements.
Benefit reports: 8
Adverse reports: 4
No-effect reports: 0
Mixed reports: 2
Unclear reports: 0
Signal confidence: 0.36
Benefits
Adverse
No Effect
High responder variability in anecdotal reports. | Step2: Moderate positive empirical signal; apply a light priority boost.
Reddit evidence: 5 mentions (confidence 0.36) across Biohackers, Supplements.
Amazon signal: 0 products scanned (confidence 0.00).
GNC signal: 0 products scanned (confidence 0.00) [BLOCKED].
post • r/Biohackers • mixed
Tongkat Ali is a Double-Sided Sword Even though it boosts Testosterone, it boosts estradiol just as much. Estradiol for weight gain is bad especially around the abdomen. It also causes fluid retention and bloating. From the study - “Result…
Open mentionpost • r/Supplements • unclear
Tongkat Ali Dosage Question I'm super confused by dosage for Tongkat Ali. The bottle I have says 1200mg root powder and 48mg of the extract. Advise is around 200-600mg with 600 being potentially toxic to the liver. They must be talking abo…
Open mentionpost • r/Supplements • benefit
Tracking Improvements and Effects of Lithium Carbonate and Tongkat Ali Thanks to everyone in the community for the replies on my previous post. Initially, I consulted a doctor about my symptoms, but they dismissed it, saying it was all in …
amazon
Amazon search for Tongkat Ali
Rating: n/a | Reviews: n/a
Open productEvidence Sources
RCT • 2021 • Adults
Small male-focused studies.
Outcome: Some signal for libido and stress marker changes.[3298,3918,4565, etc.]
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Outcome: Tier MEDIUM; humans 8, RCTs 1, meta-analyses 0.[3298,3918,4565, etc.]
Open sourceJ Sex Med
PMID 37914304 • 2023 Nov 1
Effects of Eurycoma longifolia Jack standardised water extract (Physta) on well-being of perimenopausal and postmenopausal women: protocol for a randomised, double-blinded, placebo-controlled, parallel group study.
BMJ Open
Open PubMedPMID 36231154 • 2022 Sep 20
How Internet Websites Portray Herbal Vitality Products Containing Eurycoma longifolia Jack: An Evaluation of the Quality and Risks of Online Information.
Int J Environ Res Public Health
Open PubMedPerimeterX / captcha block encountered.
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Human-study daily dose signal: 200 mg/day (confidence LOW).
Extracted from 1 dosing mentions across 1 PubMed studies (mg/day).
Imported legacy community score: 8.0/10 (heuristic mapping confidence 1.00).
Imported legacy monthly cost signal: ~$22.00.
Legacy community note: Extremely popular in men's health communities. Users frequently report improved libido, better mood, and strength gains. Some skeptics, but many devoted users with bloodwork showing improved hormone panels.
post • r/Supplements • benefit
Best Libido supplement? Tongkat Ali? Hello guys which supp helped you with Libido?
Open mentionpost • r/Biohackers • mixed
If you were building a “sexual performance stack” from scratch, what’s in it? I’m curious how this sub would architect this from first principles. Not “take Viagra and call it a day.” I mean if you were optimizing the entire sexual respons…
Open mentionpost • r/Supplements • unclear
Measuring tongkat Ali from bulk supplements Never taken this before and bought from bulk supplements on Amazon. It says take half a teaspoon which is 1g but I’ve heard that 400mg is what I should be taking so I have no idea what to do. I f…
Open mentionpost • r/Biohackers • benefit
Men, what’s been your most effective supplement for increasing confidence, drive, and libido? I know all sorts of behavioral stuff are important. Compound lifts, sunlight, etc. I’ve tried LJ100 tongkat ali (recently 200-300mg most days) an…
Open mentionpost • r/Supplements • unclear
Is this tongkat ali supplement legit, is the brand good? Thanks
Open mentioncomment • r/Biohackers • unclear
Solid info to be aware of but seconding that nearly any action that elevates T will correlate to modest rise in estrogen. Have experienced this with Tongkat ali, Boron, shilajit.. *Low dose daily cialis supports balance with T and keeping …
Open mentioncomment • r/Biohackers • unclear
i think i recall seeing one, just google tongkat ali women nih
Open mentionCommunity Sources
PUBMED • 2021 • Human evidence curation set
PMID 33541567 from Maturitas.
Outcome: See linked PubMed abstract for methods and outcomes.[3298,3918,4565, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36013514 from Medicina (Kaunas).
Outcome: See linked PubMed abstract for methods and outcomes.[3298,3918,4565, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31036522 from J Sex Med.
Outcome: See linked PubMed abstract for methods and outcomes.[3298,3918,4565, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37914304 from BMJ Open.
Outcome: See linked PubMed abstract for methods and outcomes.[3298,3918,4565, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36231154 from Int J Environ Res Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[3298,3918,4565, etc.]
Open source