Supplement
Osmoregulation, mitochondrial support, and bile acid conjugation.[1451,2972,3242, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
-8
Mixed / Neutral • confidence Moderate
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 15 • mentions 21 • links 26
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Goal alignment: Heart Health, Performance, Longevity.[121,204,308, etc.]
Dose guide: Human-study daily dose: 3000 mg/day (higher-confidence extraction from PubMed abstracts)..[121,204,308, etc.]
Category
Amino Acid
Evidence Tier
HIGH
Daily Guide
Human-study daily dose: 3000 mg/day (higher-confidence extraction from PubMed abstracts).
Dosing Guide
Human-study daily dose: 3000 mg/day (higher-confidence extraction from PubMed abstracts).[1451,, etc.]
Clinical Depth
Humans: 868 • RCTs: 132 • Meta: 19
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 989 • Interactions: 1,163
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
2392 total studies · 6 recent
Timeline
Animal-only studies
9,998
Total indexed
2,392
In vitro / tissue
1,826
Interaction signals
1,163
Safety adverse signals
989
Human studies
868
Weighted direction score: -8 (Mixed / Neutral)
High when >=2 human meta-analyses, or >=5 human RCTs with substantial human literature volume.
Animal-only studies
9,998
Total indexed
2,392
In vitro / tissue
1,826
Interaction signals
1,163
Safety adverse signals
989
Human studies
868
Randomized trials
132
Meta-analyses
19
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 29546641 • 2018 May
The Effects of an Oral Taurine Dose and Supplementation Period on Endurance Exercise Performance in Humans: A Meta-Analysis.
Sports Med
Open PubMedPMID 36615738 • 2022 Dec 24
Ergogenic Aids to Improve Physical Performance in Female Athletes: A Systematic Review with Meta-Analysis.
Nutrients
Open PubMedPMID 39796489 • 2024 Dec 27
Effect of Long-Term Taurine Supplementation on the Lipid and Glycaemic Profile in Adults with Overweight or Obesity: A Systematic Review and Meta-Analysis.
Benefit reports: 7
Adverse reports: 6
No-effect reports: 1
Mixed reports: 7
Unclear reports: 0
Signal confidence: 0.59
Benefits
Adverse
No Effect
Rising interest due to longevity discussion. | Step2: Insufficient empirical signal for a directional adjustment.
Reddit evidence: 15 mentions (confidence 0.59) across Supplements, Biohackers, sleep.
post • r/Supplements • mixed
my observation on Taurine supplementation I am 24 M at b.w of 80 kgs I’ve been training consistently for 1.5 years, and for the longest time, my squats were stuck. I plateaued hard at 100 kg for 12 reps across 3 sets. No matter what I did,…
Open mentionpost • r/Supplements • mixed
[LONG] Permanent effects after too much Taurine one time? Possible OD? **EDIT: Please read the whole post and edits before responding, This post eventually ends up in scope exceeding that of this sub, but I really think it's incredibly inf…
Open mentionpost • r/Biohackers • unclear
Should one also supplement beta alanene if taking 3-4g of daily taurine (to avoid gaba receptor becoming desensitized)? Taurine seems to downregulate gaba receptors. Beta alanene seems to upregulate them. Would it be wise to supplement bet…
amazon
Amazon search for Taurine
Rating: n/a | Reviews: n/a
Open productEvidence Sources
RCT • 2023 • Adults
Small human trials.
Outcome: Modest BP and endothelial improvements.[1451,2972,3242, etc.]
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Outcome: Tier HIGH; humans 868, RCTs 132, meta-analyses 19.[1451,2972,3242, etc.]
Open sourceNutrients
PMID 40320621 • 2025 Jun
Effects of taurine supplementation on cognitive function: a systematic review and meta-analysis of randomised controlled trials.
Int J Food Sci Nutr
Open PubMedPMID 38755142 • 2024 May 16
Taurine reduces the risk for metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
Nutr Diabetes
Open PubMedPMID 34584225 • 2022 May
Profiling inflammatory and oxidative stress biomarkers following taurine supplementation: a systematic review and dose-response meta-analysis of controlled trials.
Eur J Clin Nutr
Open PubMedPMID 37357646 • 2023 Jun
Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3-month, controlled, assessor-blinded study.
Skin Res Technol
Open PubMedPMID 11665810 • 2001
The effects of red bull energy drink on human performance and mood.
Amino Acids
Open PubMedPMID 30805607 • 2019 Mar 1
Energy Drinks Induce Acute Cardiovascular and Metabolic Changes Pointing to Potential Risks for Young Adults: A Randomized Controlled Trial.
J Nutr
Open PubMedPMID 36014800 • 2022 Aug 11
Anti-Inflammatory Diet Prevents Subclinical Colonic Inflammation and Alters Metabolomic Profile of Ulcerative Colitis Patients in Clinical Remission.
Nutrients
Open PubMedPMID 39571910 • 2025 Feb
Effect of a 12-mo intervention with whey protein powder on cognitive function in older adults with mild cognitive impairment: a randomized controlled trial.
Am J Clin Nutr
Open PubMedPMID 38776754 • 2024 Jul
Dietary sulfur amino acid restriction in humans with overweight and obesity: Evidence of an altered plasma and urine sulfurome, and a novel metabolic signature that correlates with loss of fat mass and adipose tissue gene expression.
Redox Biol
Open PubMedPMID 37289866 • 2023 Jun 9
Taurine deficiency as a driver of aging.
Science
Open PubMedPMID 38565142 • 2024 Apr 25
Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8(+) T cells.
Cell
Open PubMedPMID 37836520 • 2023 Sep 30
Functional Role of Taurine in Aging and Cardiovascular Health: An Updated Overview.
Nutrients
Open PubMedAmazon signal: 0 products scanned (confidence 0.00).
GNC signal: 0 products scanned (confidence 0.00) [BLOCKED].
PerimeterX / captcha block encountered.
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Human-study daily dose signal: 3000 mg/day (confidence HIGH).
Extracted from 5 dosing mentions across 2 PubMed studies (mg/day).
Imported legacy community score: 9.0/10 (heuristic mapping confidence 1.00).
Imported legacy monthly cost signal: ~$10.00.
Legacy community note: Exploded in popularity after 2023 Science paper. Longevity community now considers it a core supplement. Users report improved energy, better sleep, and general well-being. Extremely well-tolerated and affordable.
post • r/Supplements • mixed
My current supplement stack (creatine, taurine, PEA, astaxanthin, etc) —major improvement energy, mood, IBS and recovery. Hi everyone, I wanted to share my current supplement stack and what kind of effects I’ve experienced over the past mo…
Open mentionpost • r/sleep • benefit
Glycine + NAC + Taurine Sleep Stack = Crazy Dreams I take Glycine(3g) + NAC(1.2g) + Taurine(2g) stack about 1 hr before bed for sleep, glutathione production and methylation balance. It really works great for sleep and I see the changes th…
Open mentionpost • r/Supplements • benefit
Taurine supplementation aka STIM free Preworkout I am looking for peoples feedback on taking preworkout for longer periods, mostly focused around taurine. I posted this photo just because it’s one example of a STIM free preworkout. Have yo…
Open mentionpost • r/Supplements • mixed
Taurine supplementation in conjunction with an antidepressant SSRI or SNRI medication. Hi. I’m taking Effexor XR for anxiety. I am considering taking taurine, since it is an effective supplement for anxiety, from what I’ve read and heard f…
Open mentionpost • r/Biohackers • mixed
Can stopping taurine supplementation cause insomnia? This has happened twice now. I was taking 1.5g of taurine every morning and then eventually just forgot about it and stopped. Since stopping about 6 days ago I've had some pretty bad ins…
Open mentioncomment • r/Supplements • mixed
Awesome OP! Here is my observation: 46 female 125lbs. I have been taking Taurine for a month as well. I upped to 5mg this last week. Benefits for me: - Easily went from 3 miles to 5 miles incline treadmill walking first day of taking it. W…
Open mentioncomment • r/Supplements • benefit
Great to hear your progress , I thought I was alone, feeling that way, or maybe taurine is just too good to be true and yeah, I can vouch for the great sleep that taurine brings
Open mentionCommunity Sources
PUBMED • 2018 • Human evidence curation set
PMID 29546641 from Sports Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36615738 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39796489 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40320621 from Int J Food Sci Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38755142 from Nutr Diabetes.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 34584225 from Eur J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37357646 from Skin Res Technol.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2001 • Human evidence curation set
PMID 11665810 from Amino Acids.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30805607 from J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36014800 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 39571910 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38776754 from Redox Biol.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37289866 from Science.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38565142 from Cell.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37836520 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1451,2972,3242, etc.]
Open source