Supplement
Contains bioactive phytochemicals that may modulate stress, immune, and metabolic pathways.[3222,3378,4084, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
36/100
Early depth from human/RCT/meta counts
Community Direction
34
Positive Lean • confidence Moderate
Safety Friction
38/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 4 • mentions 8 • links 15
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Goal alignment: Stress Resilience, Mood, Immune Support, Longevity.[200,296,351, etc.]
Dose guide: Human-study daily dose: 500 mg/day (moderate-confidence extraction from PubMed abstracts)..[200,296,351, etc.]
Category
Botanical
Evidence Tier
MEDIUM
Daily Guide
Human-study daily dose: 500 mg/day (moderate-confidence extraction from PubMed abstracts).
Dosing Guide
Human-study daily dose: 500 mg/day (moderate-confidence extraction from PubMed abstracts).[,, etc.]
Clinical Depth
Humans: 4 • RCTs: 2 • Meta: 0
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 2 • Interactions: 2
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
6 total studies · 1 recent
Timeline
Total indexed
6
Human studies
4
Animal-only studies
4
In vitro / tissue
2
Randomized trials
2
Safety adverse signals
2
Weighted direction score: 34 (Positive Lean)
Medium when human evidence exists but is limited, or when animal evidence volume is substantial.
Total indexed
6
Human studies
4
Animal-only studies
4
In vitro / tissue
2
Randomized trials
2
Safety adverse signals
2
Interaction signals
2
Meta-analyses
0
Distribution of evidence by study design strength
Evidence Strength: Early
Composite of study volume, RCTs, and meta-analyses
PMID 34126996 • 2021 Jun 14
Broad Spectrum Polyphenol Supplementation from Tart Cherry Extract on Markers of Recovery from Intense Resistance Exercise.
J Int Soc Sports Nutr
Open PubMedPMID 41247121 • 2026
Effects of Tart Cherry Extract Supplementation on Plasma Urate and C-Reactive Protein Levels in Healthy Adults: a Randomized Controlled Trial.
J Diet Suppl
Open PubMedPMID 31438590 • 2019 Aug 21
Effect of Anthocyanin-Rich Tart Cherry Extract on Inflammatory Mediators and Adipokines Involved in Type 2 Diabetes in a High Fat Diet Induced Obesity Mouse Model.
Benefit reports: 5
Adverse reports: 2
No-effect reports: 0
Mixed reports: 1
Unclear reports: 0
Signal confidence: 0.41
Benefits
Adverse
No Effect
Strong positive empirical sentiment with adequate confidence; boost recommendation priority.
Reddit evidence: 6 mentions (confidence 0.41) across Supplements, HubermanLab, sleep.
Amazon signal: 0 products scanned (confidence 0.00).
GNC signal: 0 products scanned (confidence 0.00) [ERROR].
post • r/Supplements • unclear
Best tart cherry extract supplement? Does anyone have a go-to tart cherry extract supplement, ideally tested for purity/potency? I couldn't find a ConsumerLab report on tart cherry supplements. Goal is to reduce uric acid deposits in joint…
Open mentionpost • r/Supplements • benefit
I Tried 15+ Supplements for Better Sleep & Recovery - Here's What Actually Moved the Needle Hey r/supplements, wanted to share my experience after spending way too much money experimenting with sleep and recovery supplements over the past …
Open mentionpost • r/Supplements • mixed
Supplement for scalp inflammation/seboderm/psoriasis and hair loss I am a 20 year old guy. I have and have scalp inflammation/seboderm/psoriasis and hair loss. I want to buy some supplements and know if it will benefit my inflammation/seb …
amazon
Amazon search for Tart Cherry Extract
Rating: n/a | Reviews: n/a
Open productEvidence Sources
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Outcome: Tier MEDIUM; humans 4, RCTs 2, meta-analyses 0.[3222,3378,4084, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34126996 from J Int Soc Sports Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
Nutrients
PMID 30706481 • 2019 Mar
In Vitro Bioaccessibility of Tart Cherry Anthocyanins in a Health Supplement Mix Containing Mineral Clay.
J Food Sci
Open PubMedterminated
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Human-study daily dose signal: 500 mg/day (confidence MEDIUM).
Extracted from 2 dosing mentions across 1 PubMed studies (mg/day).
post • r/Supplements • adverse
Why is vitamin K2 having such a profound effect on me? for context I suffer from multiple mental health conditions. ive had bouts of psychosis which have calmed down for the most part leaving me with ocd like tendencies and a decently anhe…
Open mentionpost • r/Supplements • benefit
Need Advice For Sleep Stack I wanted to add a sleep stack to my supplement routine because I feel like I would benefit from the better quality sleep. Currently I’m taking: 1. Melatonin 0.3mg 2. L-Tryptophan 500mg 3. Tart Cherry Extract 300…
Open mentionpost • r/Supplements • unclear
Been taking two capsules of tart cherry extract per night and I’ve been having really lucid dreams. Anyone else experiencing the same for this particular brand or similar ones?
Open mentionpost • r/HubermanLab • benefit
Key Takeaways from 300 Core Huberman Lab Episodes (Analyzed with NotebookLM) Pt.2 Like many of you, I'm constantly trying to synthesise the wealth of information Andrew shares. I recently undertook a small project: I selected 50 episodes h…
Open mentionpost • r/sleep • benefit
Supplement Recommendations Hey everyone, I’m starting a supplement brand for sleep quality and was wondering if you guys have taken any supplements that you’ve found helpful? I plan to include the following ingredients: melatonin, L-theani…
Open mentioncomment • r/Supplements • unclear
*Solid* post. I would say to have the goal of getting off the tart cherry extract. Apigenim as well. From there, continue focusing on behaviour changes: - Especially a "wind-down" routine. - You didn't mention avoiding screens 1-2 hours be…
Open mentionCommunity Sources
PUBMED • 2026 • Human evidence curation set
PMID 41247121 from J Diet Suppl.
Outcome: See linked PubMed abstract for methods and outcomes.[3222,3378,4084, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31438590 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[3222,3378,4084, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30706481 from J Food Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[3222,3378,4084, etc.]
Open source