Skip to main content
Enhanced Health AIv0.6.0
QuizMy PlanCalendarEvidenceSources
Session check

© 2026 Enhanced Health AI

MD-Designed No Data Sold
QuizSearchEvidenceSourcesHow We ScorePricingTermsPrivacy
Back to Database

Supplement

Shilajit

Supports broad cellular function with category-specific mechanisms.[3226,3321,4366, etc.]

Superscript reference numbers link to the Sources bibliography.

Moderate Evidence
LongevityMetabolic HealthEnergy

Composite Rating

3.0/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

58/100

Moderate depth from human/RCT/meta counts

Community Direction

27

Positive Lean • confidence Low

Safety Friction

71/100

Moderate signal from adverse/interaction markers

Data Completeness

100%

Studies 7 • mentions 9 • links 18

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Goal alignment: Longevity, Metabolic Health, Energy.[305,339,350, etc.]

Dose guide: Human-study daily dose: 6 mg-500 mg/day (higher-confidence extraction from PubMed abstracts)..[305,339,350, etc.]

Category: other.[305,339,350, etc.]

Category

Other

Evidence Tier

MEDIUM

Daily Guide

Human-study daily dose: 6 mg-500 mg/day (higher-confidence extraction from PubMed abstracts).

Dosing Guide

Human-study daily dose: 6 mg-500 mg/day (higher-confidence extraction from PubMed abstracts).[3226,, etc.]

At-A-Glance Evidence Architecture[3226,3321,4366, etc.]

Clinical Depth

Humans: 12 • RCTs: 5 • Meta: 0

Cohort / Real-World

Cohort signals: 0

Safety Markers

Adverse signals: 15 • Interactions: 2

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

New Evidence

Trend

↑ Growing evidence base

Depth

28 total studies · 3 recent

Timeline

20192025

Top Signal Metrics[3226,3321,4366, etc.]

Total indexed

28

Animal-only studies

28

Safety adverse signals

15

In vitro / tissue

14

Human studies

12

Randomized trials

5

Community Direction Mix[305,339,350, etc.]

Weighted direction score: 27 (Positive Lean)

Benefit

Evidence Quality Summary[3226,3321,4366, etc.]

Medium when human evidence exists but is limited, or when animal evidence volume is substantial.

Total indexed

28

Animal-only studies

28

Safety adverse signals

15

In vitro / tissue

14

Human studies

12

Randomized trials

5

Interaction signals

2

Meta-analyses

0

Study Type Breakdown

Distribution of evidence by study design strength

Randomized TrialsLevel 1b5
Human Studies (other)Level 3-47
All IndexedAll levels28
58

Evidence Strength: Moderate

Composite of study volume, RCTs, and meta-analyses

Top Human Studies[3226,3321,4366, etc.]

PMID 35933897 • 2022 Oct

Shilajit extract reduces oxidative stress, inflammation, and bone loss to dose-dependently preserve bone mineral density in postmenopausal women with osteopenia: A randomized, double-blind, placebo-controlled trial.

Phytomedicine

Open PubMed

PMID 36546868 • 2024

Effects of 8 Weeks of Shilajit Supplementation on Serum Pro-c1α1, a Biomarker of Type 1 Collagen Synthesis: A Randomized Control Trial.

J Diet Suppl

Open PubMed

Community Report Frequency[305,339,350, etc.]

Benefit reports: 5

Adverse reports: 2

No-effect reports: 0

Mixed reports: 2

Unclear reports: 0

Signal confidence: 0.36

Top Reported Effects[305,339,350, etc.]

Benefits

  • energy: 3
  • better: 2
  • improved: 1
  • sleep: 1
  • recovery: 1
  • lowered: 1
  • focus: 1
  • worked: 1

Adverse

  • anxiety: 1
  • side effect: 1

No Effect

  • hard to tell: 1

Insufficient empirical signal for a directional adjustment.

Reddit evidence: 5 mentions (confidence 0.36) across Supplements, Biohackers.

Amazon signal: 0 products scanned (confidence 0.00).

GNC signal: 0 products scanned (confidence 0.00) [ERROR].

terminated

Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.

Community Evidence Examples[305,339,350, etc.]

post • r/Supplements • benefit

Added Shilajit to my stack. The changes were crazy ngl. Not here to hype anything — just sharing what actually changed for me after adding Shilajit (standardized, resin form, taken daily with water). My main issues were: • Low baseline ene…

Open mention

post • r/Supplements • unclear

Is this supplement stack too much? Adding Astaxanthin & Shilajit 33M, lift daily, generally healthy. On Rosuvastatin for cholesterol (runs in the family). Current stack: - Biotin 5,000 mcg - Vitamin D 10,000 IU + K2 (200 mcg) - Omega-3 (60…

Open mention

post • r/Supplements • unclear

Shilajit and its effects on neurological states Unlocking the potential of Shilajit in Vascular Dementia behind pathology and management - A concise review: Shilajit in VaD via cAMP/NO, inflammatory pathways

Retail Signal Examples

amazon

Amazon search for Shilajit

Rating: n/a | Reviews: n/a

Open product

Primary Source Links

Evidence Sources

  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22shilajit%22)%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22shilajit%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22shilajit%22)%20AND%20animals%5BMeSH%20Terms%5D%20NOT%20humans%5BMeSH%20Terms%5D

Scientific Evidence Notes[3226,3321,4366, etc.]

1. PubMed evidence summary: Shilajit

PUBMED • Humans + preclinical triage

Counts aggregated from automated literature sweep and tiering rules.

Outcome: Tier MEDIUM; humans 12, RCTs 5, meta-analyses 0.[3226,3321,4366, etc.]

Open source
2. Shilajit extract reduces oxidative stress, inflammation, and bone loss to dose-dependently preserve bone mineral density in postmenopausal women with osteopenia: A randomized, double-blind, placebo-controlled trial.

PUBMED • 2022 • Human evidence curation set

PMID 35933897 from Phytomedicine.

Outcome: See linked PubMed abstract for methods and outcomes.

3321,
4366

Safety and Pitfalls

  • Lower safety signal in literature, but monitor for individual response.[305,339,350, etc.]
  • Potential side effect: anxiety[305,339,350, etc.]
  • Potential side effect: side effect[305,339,350, etc.]
5 (56%)
Adverse2 (22%)
No Effect0 (0%)
Mixed2 (22%)

PMID 40573153 • 2025 Jun 19

Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shilajit Supplementation on Markers of Cardiometabolic Health, Fitness, and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind, Placebo-Controlled Trial.

Nutrients

Open PubMed

PMID 30728074 • 2019 Feb 6

The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels.

J Int Soc Sports Nutr

Open PubMed

PMID 31161927 • 2019 Aug

Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms.

J Am Coll Nutr

Open PubMed

PMID 37697053 • 2024 Jun

Do "testosterone boosters" really increase serum total testosterone? A systematic review.

Int J Impot Res

Open PubMed

PMID 35204750 • 2022 Feb 3

Novel Nutraceutical Compounds in Alzheimer Prevention.

Biomolecules

Open PubMed

Human-study daily dose signal: 6 mg-500 mg/day (confidence HIGH).

Extracted from 6 dosing mentions across 1 PubMed studies (mg/day).

Open mention

post • r/Biohackers • mixed

Shilajit lost its effect on me? Did shilajit lost its effect on me or should y cycle off it? I started taking shilajit like probably a month ago, the first weeks where amazing I had this surge in energy in vitality and vigor I woke up with…

Open mention

post • r/Supplements • benefit

should i not take this? shilajit with concerning review. A few weeks ago, I took shilajit and honey, it came in the form of sticks. I felt absolutely better than I have in years. My sex drive reappeared, I had energy, I could focus and fun…

Open mention

post • r/Supplements • adverse

Shilajit causing me to wake up too early - will this side effect fade away with time? I’ve started using this supplement and it makes me feel really good, but I wake up too early in the morning and want to fall asleep again, but it feels i…

Open mention

post • r/Biohackers • mixed

Women who biohacked severe period pain: what actually worked? (Please help!!) **SEEKING advice / recommendations / personal anecdotes (even that of a friend of a friend) / literally anything to throw at the wall!** Very grateful in advance…

Open mention

comment • r/Supplements • unclear

I'm a fan of Shilajit

Open mention

comment • r/Supplements • unclear

Shilajit has always piqued my interest. There isn’t a lot of science, but the anecdotal reviews are stellar. When/how do you take it? Fasted? First thing in the morning?

Open mention
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22shilajit%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)%20AND%20randomized%20controlled%20trial%5BPublication%20Type%5D
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22shilajit%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)%20AND%20meta-analysis%5BPublication%20Type%5D
  • https://pubmed.ncbi.nlm.nih.gov/35933897/
  • https://pubmed.ncbi.nlm.nih.gov/36546868/
  • https://pubmed.ncbi.nlm.nih.gov/40573153/
  • https://pubmed.ncbi.nlm.nih.gov/30728074/
  • https://pubmed.ncbi.nlm.nih.gov/31161927/
  • https://pubmed.ncbi.nlm.nih.gov/37697053/
  • https://pubmed.ncbi.nlm.nih.gov/35204750/
  • https://pubmed.ncbi.nlm.nih.gov/?term=Shilajit
  • Community Sources

    • https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=%22shilajit%22%20(supplement%20OR%20dosage%20OR%20stack%20OR%20side%20effects%20OR%20review)%20(subreddit%3ASupplements%20OR%20subreddit%3ANootropics%20OR%20subreddit%3ABiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3ANutrition%20OR%20subreddit%3AHubermanLab%20OR%20subreddit%3ASleep%20OR%20subreddit%3AFitness%20OR%20subreddit%3Aketoscience%20OR%20subreddit%3AStackAdvice)
    • https://old.reddit.com/r/Supplements/comments/1pkrett/added_shilajit_to_my_stack_the_changes_were_crazy/.json?raw_json=1&sort=top&limit=25
    • https://old.reddit.com/r/Supplements/comments/1qrwx2c/is_this_supplement_stack_too_much_adding/.json?raw_json=1&sort=top&limit=25
    • https://old.reddit.com/r/Supplements/comments/1qjai85/shilajit_and_its_effects_on_neurological_states/.json?raw_json=1&sort=top&limit=25
    • https://www.reddit.com/search/?q=Shilajit
    [3226,3321,4366, etc.]
    Open source
    3. Effects of 8 Weeks of Shilajit Supplementation on Serum Pro-c1α1, a Biomarker of Type 1 Collagen Synthesis: A Randomized Control Trial.

    PUBMED • 2024 • Human evidence curation set

    PMID 36546868 from J Diet Suppl.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source
    4. Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shilajit Supplementation on Markers of Cardiometabolic Health, Fitness, and Weight Loss in Men and Women with Risk Factors to Metabolic Syndrome Initiating an Exercise and Diet Intervention: A Randomized Double-Blind, Placebo-Controlled Trial.

    PUBMED • 2025 • Human evidence curation set

    PMID 40573153 from Nutrients.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source
    5. The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels.

    PUBMED • 2019 • Human evidence curation set

    PMID 30728074 from J Int Soc Sports Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source
    6. Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit Shows Induction of Microvascular and Extracellular Matrix Mechanisms.

    PUBMED • 2019 • Human evidence curation set

    PMID 31161927 from J Am Coll Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source
    7. Do "testosterone boosters" really increase serum total testosterone? A systematic review.

    PUBMED • 2024 • Human evidence curation set

    PMID 37697053 from Int J Impot Res.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source
    8. Novel Nutraceutical Compounds in Alzheimer Prevention.

    PUBMED • 2022 • Human evidence curation set

    PMID 35204750 from Biomolecules.

    Outcome: See linked PubMed abstract for methods and outcomes.[3226,3321,4366, etc.]

    Open source