Supplement
Gel-forming soluble fiber improves stool consistency and LDL markers.[1354,1643,3209, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
84/100
High depth from human/RCT/meta counts
Community Direction
34
Positive Lean • confidence Minimal
Safety Friction
92/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 10 • mentions 5 • links 20
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Goal alignment: Gut Health, Metabolic Health, Heart Health.[609,755,983, etc.]
Dose guide: Human-study daily dose: 10 mg-20000 mg/day (higher-confidence extraction from PubMed abstracts)..[609,755,983, etc.]
Category
Other
Evidence Tier
HIGH
Daily Guide
Human-study daily dose: 10 mg-20000 mg/day (higher-confidence extraction from PubMed abstracts).
Clinical Depth
Humans: 24 • RCTs: 5 • Meta: 2
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 9 • Interactions: 21
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
45 total studies · 2 recent
Timeline
Total indexed
45
Animal-only studies
34
In vitro / tissue
30
Human studies
24
Interaction signals
21
Safety adverse signals
9
Weighted direction score: 34 (Positive Lean)
High when >=2 human meta-analyses, or >=5 human RCTs with substantial human literature volume.
Total indexed
45
Animal-only studies
34
In vitro / tissue
30
Human studies
24
Interaction signals
21
Safety adverse signals
9
Randomized trials
5
Meta-analyses
2
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 36513474 • 2022 Dec
What is the efficacy of dietary, nutraceutical, and probiotic interventions for the management of gastroesophageal reflux disease symptoms? A systematic literature review and meta-analysis.
Clin Nutr ESPEN
Open PubMedPMID 10648260 • 2000 Feb
Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials.
Am J Clin Nutr
Open PubMedPMID 37078654 • 2023 Jan-Dec
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial.
Gut Microbes
Open PubMedPMID 30669509 • 2019 Jan 20
The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls.
Int J Mol Sci
Open PubMedPMID 8833174 • 1996 Mar
Psyllium husk fiber supplementation to the diets rich in soybean or coconut oil: hypocholesterolemic effect in healthy humans.
Int J Food Sci Nutr
Open PubMedPMID 7957006 • 1994 Aug
Psyllium husk fibre supplementation to soybean and coconut oil diets of humans: effect on fat digestibility and faecal fatty acid excretion.
Eur J Clin Nutr
Open PubMedPMID 15911730 • 2005 May 23
Effect of combining psyllium fiber with simvastatin in lowering cholesterol.
Arch Intern Med
Open PubMedPMID 37630852 • 2023 Aug 21
Nutrition, Physical Activity and Supplementation in Irritable Bowel Syndrome.
Nutrients
Open PubMedPMID 36041173 • 2022 Dec 22
Gastrointestinal Effects and Tolerance of Nondigestible Carbohydrate Consumption.
Adv Nutr
Open PubMedPMID 39630961 • 2024 Dec 18
Enhanced Gelation Properties and Saltiness Perception of Low-Salt Surimi Gel with Psyllium Husk Powder.
J Agric Food Chem
Open PubMedBenefit reports: 3
Adverse reports: 1
No-effect reports: 0
Mixed reports: 1
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
High real-world adherence when introduced gradually. | Step2: Insufficient empirical signal for a directional adjustment.
Reddit evidence: 0 mentions (confidence 0.00).
Amazon signal: 0 products scanned (confidence 0.00).
GNC signal: 0 products scanned (confidence 0.00) [BLOCKED].
PerimeterX / captcha block encountered.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=%22psyllium%20husk%22%20(supplement%20OR%20dosage%20OR%20stack%20OR%20side%20effects%20OR%20review)%20(subreddit%3ASupplements%20OR%20subreddit%3ANootropics%20OR%20subreddit%3ABiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3ANutrition%20OR%20subreddit%3AHubermanLab%20OR%20subreddit%3ASleep%20OR%20subreddit%3AFitness%20OR%20subreddit%3Aketoscience%20OR%20subreddit%3AStackAdvice)
Fallback search failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=comments&t=all&limit=16&q=%22psyllium%20husk%22%20(supplement%20OR%20capsule%20OR%20powder%20OR%20experience%20OR%20results%20OR%20side%20effects)
Broad search failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=new&t=all&limit=16&q=psyllium%20husk
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Human-study daily dose signal: 10 mg-20000 mg/day (confidence HIGH).
Extracted from 9 dosing mentions across 3 PubMed studies (mg/day).
Imported legacy community score: 8.0/10 (heuristic mapping confidence 1.00).
Imported legacy monthly cost signal: ~$10.00.
Legacy community note: One of the most universally recommended fiber supplements. Users report improved digestion, better satiety, and improved bloodwork. Often the first recommendation for cholesterol management before statins.
aggregate • benefit
Aggregate community signal: 5 directional mentions (benefit 3, adverse 1, no-effect 0, mixed 1).
Open mentionamazon
Amazon search for Soluble Fiber (Psyllium Husk)
Rating: n/a | Reviews: n/a
Open productEvidence Sources
Community Sources
META_ANALYSIS • 2024 • Adults
Human RCT meta-analysis.
Outcome: Consistent LDL reduction with daily intake.[1354,1643,3209, etc.]
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Outcome: Tier HIGH; humans 24, RCTs 5, meta-analyses 2.[1354,1643,3209, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36513474 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2000 • Human evidence curation set
PMID 10648260 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37078654 from Gut Microbes.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30669509 from Int J Mol Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 1996 • Human evidence curation set
PMID 8833174 from Int J Food Sci Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 1994 • Human evidence curation set
PMID 7957006 from Eur J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2005 • Human evidence curation set
PMID 15911730 from Arch Intern Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37630852 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36041173 from Adv Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39630961 from J Agric Food Chem.
Outcome: See linked PubMed abstract for methods and outcomes.[1354,1643,3209, etc.]
Open source