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Supplement

Holy Basil (Tulsi / Ocimum tenuiflorum)

Eugenol, rosmarinic acid, ursolic acid modulate cortisol, reduce NF-κB activation, inhibit COX-2, enhance insulin sensitivity, and provide adaptogenic stress protection.[2047,2784,2819, etc.]

Superscript reference numbers link to the Sources bibliography.

Early Research
Stress ResilienceBlood SugarImmune SupportInflammationalias: tulsialias: Ocimum sanctumalias: sacred basil

Composite Rating

3.2/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

49/100

Moderate depth from human/RCT/meta counts

Community Direction

9

Mixed / Neutral • confidence Moderate

Safety Friction

0/100

Sparse signal from adverse/interaction markers

Data Completeness

100%

Studies 3 • mentions 8 • links 5

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Goal alignment: Stress Resilience, Blood Sugar, Immune Support, Inflammation.[2047,2784,2819, etc.]

Dose guide: 300-600 mg extract, or 2-3 g dried herb as tea, daily.[2047,2784,2819, etc.]

Category: botanical.[2047,2784,2819, etc.]

Category

Botanical

Evidence Tier

PRELIMINARY

Daily Guide

300-600 mg extract, or 2-3 g dried herb as tea, daily

Dosing Guide

300-600 mg extract, or 2-3 g dried herb as tea, daily[2047,,, etc.]

At-A-Glance Evidence Architecture[2047,2784,2819, etc.]

Clinical Depth

Humans: 3 • RCTs: 3 • Meta: 1

Cohort / Real-World

Cohort signals: 0

Safety Markers

Adverse signals: 0 • Interactions: 0

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

Aging Evidence

Trend

· Limited trend data

Depth

3 total studies

Timeline

20112017

Top Signal Metrics[2047,2784,2819, etc.]

Total indexed

3

Human studies

3

Randomized trials

3

Meta-analyses

1

Cohort signals

0

Mechanistic signals

0

Community Direction Mix[6200]

Weighted direction score: 9 (Mixed / Neutral)

Benefit4 (50%)

Evidence Quality Summary[2047,2784,2819, etc.]

Total indexed

3

Human studies

3

Randomized trials

3

Meta-analyses

1

Cohort signals

0

Mechanistic signals

0

Study Type Breakdown

Distribution of evidence by study design strength

Meta-AnalysesLevel 1a1
Randomized TrialsLevel 1b3
All IndexedAll levels3
49

Evidence Strength: Moderate

Composite of study volume, RCTs, and meta-analyses

Top Human Studies[2047,2784,2819, etc.]

PMID 28684398 • 2017

Tulsi (Ocimum sanctum) for stress-related conditions: systematic review of RCTs

SYSTEMATIC_REVIEW

Open PubMed

PMID 28483451 • 2017

Tulsi extract and metabolic syndrome parameters: RCT

RCT

Open PubMed

PMID 21739034 • 2011

Holy basil and immune response: a randomized trial

RCT

Open PubMed

Community Report Frequency[6200]

Benefit reports: 4

Adverse reports: 3

No-effect reports: 0

Mixed reports: 1

Unclear reports: 0

Signal confidence: 0.63

Top Reported Effects[6200]

Benefits

  • stress relief: 1
  • calm energy: 1
  • pleasant tea: 1
  • blood sugar control: 1

Adverse

  • fertility concern: 1
  • thyroid worry: 1
  • mild effect: 1

No Effect

  • insufficient no-effect reports captured: 0

Premier Ayurvedic adaptogen. Tulsi tea is widely consumed in India. Excellent for stress support with metabolic benefits.

Community Evidence Examples[6200]

aggregate • benefit

Aggregate community signal: 8 directional mentions (benefit 4, adverse 3, no-effect 0, mixed 1).

Open mention

Retail Signal Examples

amazon

Amazon search for Holy Basil (Tulsi / Ocimum tenuiflorum)

Rating: n/a | Reviews: n/a

Open product

Primary Source Links

Evidence Sources

  • https://pubmed.ncbi.nlm.nih.gov/28684398/
  • https://pubmed.ncbi.nlm.nih.gov/28483451/
  • https://pubmed.ncbi.nlm.nih.gov/21739034/
  • https://pubmed.ncbi.nlm.nih.gov/?term=Holy%20Basil%20(Tulsi%20%2F%20Ocimum%20tenuiflorum)

Community Sources

  • https://www.reddit.com/search/?q=Holy%20Basil%20(Tulsi%20%2F%20Ocimum%20tenuiflorum)

Scientific Evidence Notes[2047,2784,2819, etc.]

1. Tulsi (Ocimum sanctum) for stress-related conditions: systematic review of RCTs

PUBMED • 2017 • Human evidence curation set

PMID 28684398 from SYSTEMATIC_REVIEW.

Outcome: See linked PubMed abstract for methods and outcomes.[2047,2784,2819, etc.]

Open source
2. Tulsi extract and metabolic syndrome parameters: RCT

PUBMED • 2017 • Human evidence curation set

PMID 28483451 from RCT.

Outcome: See linked PubMed abstract for methods and outcomes.[2047,2784,2819, etc.]

Open source
2784
2819

Safety and Pitfalls

  • May lower blood sugar. Traditionally safe, consumed as tea in India for millennia. Anti-fertility effect in animal studies.[2047,2784,2819, etc.]
  • Potential side effect: nausea (rare)[2047,2784,2819, etc.]
  • Potential side effect: liver enzyme changes at very high doses[2047,2784,2819, etc.]
  • Use caution with condition: pregnancy (possible anti-fertility)[2047,2784,2819, etc.]
  • Use caution with condition: hypothyroidism[2047,2784,2819, etc.]
  • Interaction check: anticoagulants[2047,2784,2819, etc.]
  • Interaction check: diabetes medication (additive)[2047,2784,2819, etc.]
Adverse
3 (38%)
No Effect0 (0%)
Mixed1 (13%)
3. Holy basil and immune response: a randomized trial

PUBMED • 2011 • Human evidence curation set

PMID 21739034 from RCT.

Outcome: See linked PubMed abstract for methods and outcomes.[2047,2784,2819, etc.]

Open source