Supplement
Rich in immunoglobulins (IgG), lactoferrin, growth factors (IGF-1, TGF-β), and PRPs that strengthen mucosal immunity, repair gut epithelium, and reduce intestinal permeability.[1444,1719,2357, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
45/100
Moderate depth from human/RCT/meta counts
Community Direction
-4
Mixed / Neutral • confidence Moderate
Safety Friction
0/100
Sparse signal from adverse/interaction markers
Data Completeness
100%
Studies 3 • mentions 7 • links 5
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Goal alignment: Immune Support, Gut Health, Recovery, Performance.[1444,1719,2357, etc.]
Dose guide: 10-40 g/day powder, or 500 mg-5 g IgG concentrate capsules.[1444,1719,2357, etc.]
Category
Other
Evidence Tier
PRELIMINARY
Daily Guide
10-40 g/day powder, or 500 mg-5 g IgG concentrate capsules
Clinical Depth
Humans: 3 • RCTs: 2 • Meta: 1
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 0 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
· Limited trend data
Depth
3 total studies
Timeline
Total indexed
3
Human studies
3
Randomized trials
2
Meta-analyses
1
Cohort signals
0
Mechanistic signals
0
Weighted direction score: -4 (Mixed / Neutral)
Total indexed
3
Human studies
3
Randomized trials
2
Meta-analyses
1
Cohort signals
0
Mechanistic signals
0
Distribution of evidence by study design strength
Evidence Strength: Moderate
Composite of study volume, RCTs, and meta-analyses
PMID 25202189 • 2014
Bovine colostrum supplementation and exercise: systematic review
META_ANALYSIS
Open PubMedPMID 17096151 • 2006
Bovine colostrum and URTI in athletes: randomized trial
RCT
Open PubMedPMID 11502313 • 2001
Bovine colostrum and intestinal permeability in NSAID users
RCT
Open PubMedBenefit reports: 3
Adverse reports: 3
No-effect reports: 0
Mixed reports: 1
Unclear reports: 0
Signal confidence: 0.60
Benefits
Adverse
No Effect
Growing interest in gut health community. Key benefit: protecting gut barrier during exercise and NSAID use. IGF-1 in colostrum is largely digested.
aggregate • unclear
Aggregate community signal: 7 directional mentions (benefit 3, adverse 3, no-effect 0, mixed 1).
Open mentionamazon
Amazon search for Bovine Colostrum
Rating: n/a | Reviews: n/a
Open productPUBMED • 2014 • Human evidence curation set
PMID 25202189 from META_ANALYSIS.
Outcome: See linked PubMed abstract for methods and outcomes.[1444,1719,2357, etc.]
Open sourcePUBMED • 2006 • Human evidence curation set
PMID 17096151 from RCT.
Outcome: See linked PubMed abstract for methods and outcomes.[1444,1719,2357, etc.]
Open sourcePUBMED • 2001 • Human evidence curation set
PMID 11502313 from RCT.
Outcome: See linked PubMed abstract for methods and outcomes.[1444,1719,2357, etc.]
Open source