Immune SupportLongevityHeart HealthStress Resiliencealias: Huang Qialias: Astragalus rootalias: astragaloside IV
Composite Rating
3.8/5
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
9
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 8 • links 106
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
500-1000 mg root extract, or 2-4 g dried root powder daily
Dosing Guide
500-1000 mg root extract, or 2-4 g dried root powder daily[1471,1516,1519, etc.]
Safety and Pitfalls
Cornerstone of Traditional Chinese Medicine. Immune-stimulating — not appropriate for autoimmune conditions. Injection studies have limited applicability to oral supplements.[237,338,365, etc.]
Potential side effect: GI upset[237,338,365, etc.]
Potential side effect: diarrhea[237,338,365, etc.]
Potential side effect: nasal dryness[237,338,365, etc.]
Use caution with condition: autoimmune disease[237,338,365, etc.]
Use caution with condition: organ transplant recipients[237,338,365, etc.]
A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study.
SHPro(®) (mixture of Angelica gigas and Astragalus membranaceus) in men with lower urinary tract symptoms: A randomized, double-blind, placebo-controlled clinical trial.
Can We Slow Down Biological Age Progression? Study Protocol for the proBNPage Reduction (PBAR) Randomized, Double-Blind, Placebo-Controlled Trial (Effects of 4 "Anti-Aging" Food Supplements in Healthy Older Adults).
Oxaliplatin-based chemotherapy combined with traditional medicines for neutropenia in colorectal cancer: A meta-analysis of the contributions of specific plants.
A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections.
Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study.
A Randomized Controlled Study to Observe the Efficacy of External Treatment With a Traditional Chinese Medicine Herbal Ointment on Malignant Plural Effusion: Outcome Report and Design Review.
Younger individuals with good mitochondrial function: 1
No Effect
insufficient no-effect reports captured: 0
Fundamental TCM tonic herb. TA-65 (cycloastragenol) marketed heavily for telomere lengthening — intriguing but very expensive and preliminary. Standard root extract affordable and well-tolerated. | Step2: Insufficient empirical signal for a directional adjustment.
Reddit evidence: 0 mentions (confidence 0.00) across Supplements.
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Imported legacy community score: 8.0/10 (heuristic mapping confidence 1.00).
Legacy community note: Gaining rapid popularity in longevity and fitness communities. Users report improved energy and exercise endurance. Premium price point. MitoPure (Timeline) is the most studied brand.
Astragalus, organo oil, betaglucan, Quercetin and chaga on the same day, is it too much? I don’t want to overdo and harm the body. Be kind to my liver. What do you think, should I alter them?
Can someone that understands compounds and ingredients within supplements very well, please explain if this supplement is worth taking? Here are the listed ingridients: | **30**Servings Per Container: | |:-| | **6 Capsules**Serving Size: |…
1. Astragalus injection as adjuvant in heart failure: MA of 62 RCTs
META_ANALYSIS • 2019 • Adults
62 RCTs with 5162 heart failure patients.
Outcome: Astragalus injection adjunct to conventional therapy significantly improved cardiac output (+23%), LVEF (+5.8%), and 6MWD in chronic heart failure.[1471,1516,1519, etc.]
Open source 2. Astragalus and immune function in elderly: RCT
RCT • 2009 • Adults
120 elderly adults.
Outcome: Astragalus membranaceus 500 mg/day for 2 months significantly increased T-cell counts (CD3+, CD4+), NK cell activity, and IFN-γ production.[1471,1516,1519, etc.]
Open source 3. Cycloastragenol and telomerase activation: in vivo/in vitro review
MECHANISTIC • 2011 • Adults
Preclinical data across cell lines and animal models.
Outcome: Cycloastragenol (TA-65) activates telomerase in T-cells and endothelial cells, reduces critically short telomeres; proposed anti-aging mechanism of astragalus.[1471,1516,1519, etc.]
Open source 4. PubMed evidence summary: Astragalus
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Open source 5. Effects of TA-65 on telomere length, functional outcomes, and inflammation: a systematic review and meta-analysis.
PUBMED • 2025 • Human evidence curation set
PMID 41286474 from Cell biology and toxicology.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 6. A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study.
PUBMED • 2024 • Human evidence curation set
PMID 39275278 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 7. Identifying immunostimulatory herbal supplements that may flare autoimmune skin diseases: a systematic scoping review.
PUBMED • 2025 • Human evidence curation set
PMID 41475897 from Lupus science & medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 8. Nutritional supplements and their effect on glucose control.
PUBMED • 2011 • Human evidence curation set
PMID 21298562 from Current diabetes reports.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 9. SHPro(®) (mixture of Angelica gigas and Astragalus membranaceus) in men with lower urinary tract symptoms: A randomized, double-blind, placebo-controlled clinical trial.
PUBMED • 2025 • Human evidence curation set
PMID 41184148 from Investigative and clinical urology.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 10. Can We Slow Down Biological Age Progression? Study Protocol for the proBNPage Reduction (PBAR) Randomized, Double-Blind, Placebo-Controlled Trial (Effects of 4 "Anti-Aging" Food Supplements in Healthy Older Adults).
PUBMED • 2023 • Human evidence curation set
PMID 37915546 from Clinical interventions in aging.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 11. Astragaloside IV Supplementation Promotes A Neuroprotective Effect in Experimental Models of Neurological Disorders: A Systematic Review.
PUBMED • 2019 • Human evidence curation set
PMID 30207235 from Current neuropharmacology.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 12. A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study.
PUBMED • 2016 • Human evidence curation set
PMID 26950204 from Rejuvenation research.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 13. Efficacy of Astragalus Membranaceus (Huang Qi) for Cancer-Related Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Studies.
PUBMED • 2025 • Human evidence curation set
PMID 40302232 from Integrative cancer therapies.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 14. Efficacy and safety of astragalus polysaccharides in patients with malignant tumors: A systematic review and meta-analysis.
PUBMED • 2025 • Human evidence curation set
PMID 40208321 from Naunyn-Schmiedeberg's archives of pharmacology.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 15. Efficacy and Safety of Huangqi Guizhi Wuwu Decoction for Oxaliplatin-Induced Peripheral Neurotoxicity: A Systematic Review and Meta-Analysis.
PUBMED • 2024 • Human evidence curation set
PMID 37820675 from Alternative therapies in health and medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 16. Oxaliplatin-based chemotherapy combined with traditional medicines for neutropenia in colorectal cancer: A meta-analysis of the contributions of specific plants.
PUBMED • 2016 • Human evidence curation set
PMID 27497028 from Critical reviews in oncology/hematology.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 17. A Randomized Controlled Trial Comparing a New D-Mannose-based Dietary Supplement to Placebo for the Treatment of Uncomplicated Escherichia coli Urinary Tract Infections.
PUBMED • 2023 • Human evidence curation set
PMID 36621376 from European urology focus.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 18. Modified Yupingfeng formula for the treatment of stable chronic obstructive pulmonary disease: a systematic review of randomized controlled trials.
PUBMED • 2014 • Human evidence curation set
PMID 24653547 from African journal of traditional, complementary, and alternative medicines : AJTCAM.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 19. Effects of Astragalus membranaceus and Panax notoginseng Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study.
PUBMED • 2026 • Human evidence curation set
PMID 41683325 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 20. Neural correlates of traditional Chinese medicine induced advantageous risk-taking decision making.
PUBMED • 2009 • Human evidence curation set
PMID 19679384 from Brain and cognition.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 21. Astragalosides Supplementation Enhances Intrinsic Muscle Repair Capacity Following Eccentric Exercise-Induced Injury.
PUBMED • 2022 • Human evidence curation set
PMID 36297022 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 22. Repressed Exercise-Induced Hepcidin Levels after Danggui Buxue Tang Supplementation in Male Recreational Runners.
PUBMED • 2018 • Human evidence curation set
PMID 30231484 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 23. Standardized astragalus extract for attenuation of the immunosuppression induced by strenuous physical exercise: randomized controlled trial.
PUBMED • 2021 • Human evidence curation set
PMID 34271953 from Journal of the International Society of Sports Nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 24. A Randomized Controlled Study to Observe the Efficacy of External Treatment With a Traditional Chinese Medicine Herbal Ointment on Malignant Plural Effusion: Outcome Report and Design Review.
PUBMED • 2017 • Human evidence curation set
PMID 27431570 from Integrative cancer therapies.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 25. TA-65, A Telomerase Activator improves Cardiovascular Markers in Patients with Metabolic Syndrome.
PUBMED • 2018 • Human evidence curation set
PMID 29546832 from Current pharmaceutical design.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 26. Effects of Astragalus Extract Mixture HT042 on Height Growth in Children with Mild Short Stature: A Multicenter Randomized Controlled Trial.
PUBMED • 2018 • Human evidence curation set
PMID 29130588 from Phytotherapy research : PTR.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 27. The safety and efficacy of a dietary herbal supplement and gallic acid for weight loss.
PUBMED • 2007 • Human evidence curation set
PMID 17472485 from Journal of medicinal food.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 28. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis.
PUBMED • 2010 • Human evidence curation set
PMID 19504468 from Phytotherapy research : PTR.
Outcome: See linked PubMed abstract for methods and outcomes.[1471,1516,1519, etc.]
Open source 29. Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia.
RCT • 2007 • PubMed indexed study
PMID 17609906 from Chinese journal of integrative medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 30. The protective effects of the traditional Chinese herbs against renal damage induced by extracorporeal shock wave lithotripsy: a clinical study.
RCT • 2011 • PubMed indexed study
PMID 20607528 from Urological research.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 31. [Clinical and experimental study of the effect of kang er xin-I on viral myocarditis].
RCT • 1991 • PubMed indexed study
PMID 1659497 from Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 32. [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor].
RCT • 2002 • PubMed indexed study
PMID 12592686 from Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 33. [Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer].
RCT • 2003 • PubMed indexed study
PMID 14626183 from Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 34. [Observation on effect of supplementary treatment by Astragalus injection in treating senile pulmonary tuberculosis patients].
RCT • 2001 • PubMed indexed study
PMID 12577419 from Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 35. [Effects of yiqi huoxue method on cardiac function in patients with congestive heart failure].
RCT • 2006 • PubMed indexed study
PMID 16841677 from Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1471,1516,1519, etc.]
Open source 36. Bibliometric and content analysis of the Cochrane Complementary Medicine Field specialized register of controlled trials.
RCT • 2013 • PubMed indexed study
PMID 23826877 from Systematic reviews.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 6.5/10.[1471,1516,1519, etc.]
Open source 37. Chemical and biological assessment of Angelica herbal decoction: comparison of different preparations during historical applications.
COHORT • 2012 • PubMed indexed study
PMID 22902230 from Phytomedicine : international journal of phytotherapy and phytopharmacology.
Outcome: Study design: COHORT. Quality score: 6.1/10.[1471,1516,1519, etc.]
Open source 38. The Effects of Natural Product-Derived Extracts for Longitudinal Bone Growth: An Overview of In Vivo Experiments.
PUBMED • 2023 • PubMed indexed study
PMID 38068932 from International journal of molecular sciences.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1471,1516,1519, etc.]
Open source 39. Immunity: plants as effective mediators.
PUBMED • 2014 • PubMed indexed study
PMID 24564587 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.6/10.[1471,1516,1519, etc.]
Open source 40. Comparative evaluation of polysaccharides isolated from Astragalus, oyster mushroom, and yacon as inhibitors of α-glucosidase.
COHORT • 2014 • PubMed indexed study
PMID 24863354 from Chinese journal of natural medicines.
Outcome: Study design: COHORT. Quality score: 5.6/10.[1471,1516,1519, etc.]
Open source 41. Effects of herbal preparation Equiguard on hormone-responsive and hormone-refractory prostate carcinoma cells: mechanistic studies.
COHORT • 2002 • PubMed indexed study
PMID 11894110 from International journal of oncology.
Outcome: Study design: COHORT. Quality score: 5.5/10.[1471,1516,1519, etc.]
Open source 42. Impacts of Selected Dietary Nutrient Intakes on Skeletal Muscle Insulin Sensitivity and Applications to Early Prevention of Type 2 Diabetes.
PUBMED • 2021 • PubMed indexed study
PMID 33418570 from Advances in nutrition (Bethesda, Md.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.3/10.[1471,1516,1519, etc.]
Open source 43. Structural changes of polysaccharides from Astragulus after honey processing and their bioactivities on human gut microbiota.
PUBMED • 2023 • PubMed indexed study
PMID 37358876 from Journal of the science of food and agriculture.
Outcome: Study design: OTHER. Quality score: 5.3/10.[1471,1516,1519, etc.]
Open source 44. Chinese nonmedicinal herbal diet and risk of nasopharyngeal carcinoma: A population-based case-control study.
COHORT • 2019 • PubMed indexed study
PMID 31544233 from Cancer.
Outcome: Study design: CASE_CONTROL. Quality score: 5.2/10.[1471,1516,1519, etc.]
Open source 45. Benefit of an association of an antioxidative substrate and a traditional chinese medicine on telomere elongation.
PUBMED • 2019 • PubMed indexed study
PMID 32133978 from Cellular and molecular biology (Noisy-le-Grand, France).
Outcome: Study design: OTHER. Quality score: 5.2/10.[1471,1516,1519, etc.]
Open source 46. Cycloastragenol as an Exogenous Enhancer of Chondrogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells. A Morphological Study.
PUBMED • 2020 • PubMed indexed study
PMID 32028592 from Cells.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1471,1516,1519, etc.]
Open source 47. A review of food hydrocolloids on cardiovascular health: Alginate, astragalus polysaccharides, carrageenan, fucoidan, lunasin, and psyllium.
PUBMED • 2025 • PubMed indexed study
PMID 40409656 from International journal of biological macromolecules.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1471,1516,1519, etc.]
Open source 48. Renal Health Through Medicine-Food Homology: A Comprehensive Review of Botanical Micronutrients and Their Mechanisms.
PUBMED • 2024 • PubMed indexed study
PMID 39458524 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1471,1516,1519, etc.]
Open source 49. Lawsuit challenges anti-ageing claims.
PUBMED • 2012 • PubMed indexed study
PMID 22859181 from Nature.
Outcome: Study design: OTHER. Quality score: 5.0/10.[1471,1516,1519, etc.]
Open source 50. Recent reports in the biggest herbal genus, Astragalus, in Iran; with a special viewpoint on tragacanth gum production.
PUBMED • 2024 • PubMed indexed study
PMID 37462408 from Natural product research.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1471,1516,1519, etc.]
Open source 51. Integrative medicine considerations for convalescence from mild-to-moderate COVID-19 disease.
PUBMED • 2022 • PubMed indexed study
PMID 33358750 from Explore (New York, N.Y.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1471,1516,1519, etc.]
Open source 52. Investigation of antioxidant interactions between Radix Astragali and Cimicifuga foetida and identification of synergistic antioxidant compounds.
PUBMED • 2014 • PubMed indexed study
PMID 24498048 from PloS one.
Outcome: Study design: OTHER. Quality score: 4.7/10.[1471,1516,1519, etc.]
Open source 53. Herbal medicine for sports: a review.
PUBMED • 2018 • PubMed indexed study
PMID 29568244 from Journal of the International Society of Sports Nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 54. Calycosin orchestrates the functions of Danggui Buxue Tang, a Chinese herbal decoction composing of Astragali Radix and Angelica Sinensis Radix: An evaluation by using calycosin-knock out herbal extract.
PUBMED • 2015 • PubMed indexed study
PMID 25796405 from Journal of ethnopharmacology.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 55. Creating a Vaccine-like Supplement against Respiratory Infection Using Recombinant Bacillus subtilis Spores Expressing SARS-CoV-2 Spike Protein with Natural Products.
PUBMED • 2023 • PubMed indexed study
PMID 37446658 from Molecules (Basel, Switzerland).
Outcome: Study design: OTHER. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 56. Inhibitory effect of emodin and Astragalus polysaccharide on the replication of HBV.
PUBMED • 2009 • PubMed indexed study
PMID 19960563 from World journal of gastroenterology.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 57. Chemical and biological assessment of a chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: Determination of drug ratio in having optimized properties.
PUBMED • 2006 • PubMed indexed study
PMID 16569074 from Journal of agricultural and food chemistry.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 58. A Pilot EEG Study on the Acute Neurophysiological Effects of Single-Dose Astragaloside IV in Healthy Young Adults.
PUBMED • 2025 • PubMed indexed study
PMID 40806010 from Nutrients.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1471,1516,1519, etc.]
Open source 59. Integrating dietary supplements into cancer care.
PUBMED • 2013 • PubMed indexed study
PMID 23439656 from Integrative cancer therapies.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1471,1516,1519, etc.]
Open source 60. Herbal interactions with anticancer drugs: mechanistic and clinical considerations.
PUBMED • 2010 • PubMed indexed study
PMID 20345351 from Current medicinal chemistry.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1471,1516,1519, etc.]
Open source 61. [Neurological syndromes linked with the intake of plants and fungi containing a toxic component (I). Neurotoxic syndromes caused by the ingestion of plants, seeds and fruits].
PUBMED • 2003 • PubMed indexed study
PMID 12717675 from Revista de neurologia.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1471,1516,1519, etc.]
Open source 62. Pharmacological activity of cardiovascular agents from herbal medicine.
PUBMED • 2007 • PubMed indexed study
PMID 17979689 from Cardiovascular & hematological agents in medicinal chemistry.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1471,1516,1519, etc.]
Open source 63. [Regulative mechanisms of tubular epithelial to mesenchymal transition and interventional effects of Chinese herbal medicine].
PUBMED • 2013 • PubMed indexed study
PMID 23724667 from Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1471,1516,1519, etc.]
Open source 64. Synthesis and evaluation of a novel water-soluble high Se-enriched Astragalus polysaccharide nanoparticles.
PUBMED • 2018 • PubMed indexed study
PMID 30170361 from International journal of biological macromolecules.
Outcome: Study design: OTHER. Quality score: 4.4/10.[1471,1516,1519, etc.]
Open source 65. Astragenol alleviates neuroinflammation and improves Parkinson's symptoms through amino acid metabolism pathway and inhibition of ferroptosis.
PUBMED • 2025 • PubMed indexed study
PMID 40306495 from Journal of ethnopharmacology.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 66. Ameliorating effect of bovine bone collagen peptide/astragalus polysaccharide combination on bone mineral density and its underlying mechanism.
PUBMED • 2026 • PubMed indexed study
PMID 41636696 from Food & function.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 67. Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF-1 pathway.
PUBMED • 2023 • PubMed indexed study
PMID 38018587 from Immunity, inflammation and disease.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 68. Herb pair of Huangqi-Danggui exerts anti-tumor immunity to breast cancer by upregulating PIK3R1.
PUBMED • 2024 • PubMed indexed study
PMID 38863309 from Animal models and experimental medicine.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 69. Distribution Characteristics of Nutritional Elements and Combined Health Risk of Heavy Metals in Medicinal Tea from Genuine Producing Area of China.
PUBMED • 2023 • PubMed indexed study
PMID 35294744 from Biological trace element research.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 70. [Formulation patterns and potential targets of traditional Chinese medicine in the treatment of pneumoconiosis based on network pharmacology].
PUBMED • 2025 • PubMed indexed study
PMID 41073340 from Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
Outcome: Study design: OTHER. Quality score: 4.3/10.[1471,1516,1519, etc.]
Open source 71. Desulfovibrio vulgaris, a potent acetic acid-producing bacterium, attenuates nonalcoholic fatty liver disease in mice.
ANIMAL • 2021 • PubMed indexed study
PMID 34125646 from Gut microbes.
Outcome: Study design: ANIMAL. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 72. Water extract of ginseng and astragalus regulates macrophage polarization and synergistically enhances DDP's anticancer effect.
PUBMED • 2019 • PubMed indexed study
PMID 30529424 from Journal of ethnopharmacology.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 73. Proanthocyanidins Promote Endothelial Cell Viability and Angiogenesis.
PUBMED • 2022 • PubMed indexed study
PMID 35170488 from Journal of cardiovascular pharmacology.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 74. Immune Competence and Minimizing Susceptibility to COVID-19 and Other Immune System Threats.
PUBMED • 2020 • PubMed indexed study
PMID 33245701 from Alternative therapies in health and medicine.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 75. [Safety evaluation of heavy metals contaminated Astragalus membranaceus using health risk assessment model].
PUBMED • 2019 • PubMed indexed study
PMID 31602858 from Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 76. Integrated network pharmacology and molecular docking strategy to explore the mechanism of medicinal and edible Astragali Radix-Atractylodis Macrocephalae Rhizoma acting on pneumonia via immunomodulation.
PUBMED • 2020 • PubMed indexed study
PMID 33025599 from Journal of food biochemistry.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 77. Fe(3)O(4)@ Astragalus Polysaccharide Core-Shell Nanoparticles for Iron Deficiency Anemia Therapy and Magnetic Resonance Imaging in Vivo.
PUBMED • 2019 • PubMed indexed study
PMID 30801182 from ACS applied materials & interfaces.
Outcome: Study design: OTHER. Quality score: 4.2/10.[1471,1516,1519, etc.]
Open source 78. Novel herbal medicine LA16001 ameliorates cisplatin-induced anorexia.
PUBMED • 2018 • PubMed indexed study
PMID 29207134 from Molecular medicine reports.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1471,1516,1519, etc.]
Open source 79. Occurrence of ochratoxin A in Astragalus propinquus root and its transfer to decoction.
PUBMED • 2018 • PubMed indexed study
PMID 29696523 from Mycotoxin research.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1471,1516,1519, etc.]
Open source 80. [Complex network analysis of law on Chinese herbal drugs intervention on radiation induced lung injury].
PUBMED • 2018 • PubMed indexed study
PMID 30111064 from Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1471,1516,1519, etc.]
Open source 81. Prediction of Radix Astragali Immunomodulatory Effect of CD80 Expression from Chromatograms by Quantitative Pattern-Activity Relationship.
PUBMED • 2017 • PubMed indexed study
PMID 28337449 from BioMed research international.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1471,1516,1519, etc.]
Open source 82. Dietary supplementation with Astragalus polysaccharide enhances ileal digestibilities and serum concentrations of amino acids in early weaned piglets.
PUBMED • 2009 • PubMed indexed study
PMID 18622730 from Amino acids.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1471,1516,1519, etc.]
Open source 83. Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity.
PUBMED • 2011 • PubMed indexed study
PMID 21468543 from International journal of oncology.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1471,1516,1519, etc.]
Open source 84. [Regulatory effect of ligustrazine and Radix astragalus on RANTES and receptor CCR5 expression in the genesis and development process of endometriosis].
PUBMED • 2008 • PubMed indexed study
PMID 19213338 from Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1471,1516,1519, etc.]
Open source 85. Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity.
PUBMED • 2003 • PubMed indexed study
PMID 12912963 from Clinical cancer research : an official journal of the American Association for Cancer Research.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1471,1516,1519, etc.]
Open source 86. Ask the doctor. Since having a heart attack, I have been taking lisinopril, Zocor, Plavix, aspirin, a multivitamin, fish oil, calcium, vitamin D, coenzyme Q(10), chia oil, B-50 complex, grape seed extract, Nu-Zymes, Natural Energy supplement, Super C22 and astragalus. I am thinking of taking a brain booster called Procera AVH. Will it interfere with my heart medications?
PUBMED • 2009 • PubMed indexed study
PMID 19685568 from Harvard heart letter : from Harvard Medical School.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1471,1516,1519, etc.]
Open source 87. Astragaloside IV as a novel CXCR4 antagonist alleviates osteoarthritis in the knee of monosodium iodoacetate-induced rats.
ANIMAL • 2023 • PubMed indexed study
PMID 36403512 from Phytomedicine : international journal of phytotherapy and phytopharmacology.
Outcome: Study design: ANIMAL. Quality score: 3.9/10.[1471,1516,1519, etc.]
Open source 88. Effects of treatment with Astragalus Membranaceus on function of rat leydig cells.
ANIMAL • 2015 • PubMed indexed study
PMID 26231491 from BMC complementary and alternative medicine.
Outcome: Study design: ANIMAL. Quality score: 3.1/10.[1471,1516,1519, etc.]
Open source 89. Flavonoids from Radix Astragali induce the expression of erythropoietin in cultured cells: a signaling mediated via the accumulation of hypoxia-inducible factor-1α.
IN_VITRO • 2011 • PubMed indexed study
PMID 21309574 from Journal of agricultural and food chemistry.
Outcome: Study design: IN_VITRO. Quality score: 3.1/10.[1471,1516,1519, etc.]
Open source 90. Effects of Astragalus membranaceus with supplemental calcium on bone mineral density and bone metabolism in calcium-deficient ovariectomized rats.
ANIMAL • 2013 • PubMed indexed study
PMID 23136088 from Biological trace element research.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1471,1516,1519, etc.]
Open source 91. BreastDefend™ prevents breast-to-lung cancer metastases in an orthotopic animal model of triple-negative human breast cancer.
ANIMAL • 2012 • PubMed indexed study
PMID 22842551 from Oncology reports.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1471,1516,1519, etc.]
Open source 92. Astragalus Shiitake-A Novel Functional Food with High Polysaccharide Content and Anti-Proliferative Activity in a Colorectal Carcinoma Cell Line.
IN_VITRO • 2022 • PubMed indexed study
PMID 35684133 from Nutrients.
Outcome: Study design: IN_VITRO. Quality score: 3.0/10.[1471,1516,1519, etc.]
Open source 93. Semen Astragali Complanati- and Rhizoma Cibotii-enhanced bone formation in osteoporosis rats.
ANIMAL • 2013 • PubMed indexed study
PMID 23782721 from BMC complementary and alternative medicine.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1471,1516,1519, etc.]
Open source 94. Exploring the Prebiotic Potential of Fermented Astragalus Polysaccharides on Gut Microbiota Regulation In Vitro.
IN_VITRO • 2024 • PubMed indexed study
PMID 39709319 from Current microbiology.
Outcome: Study design: IN_VITRO. Quality score: 2.8/10.[1471,1516,1519, etc.]
Open source 95. Astragalus Polysaccharide Mediates Immunomodulatory Effects on Crosstalk between Human Peripheral Blood Mononuclear Cells and Ovarian Cancer Cell Line.
IN_VITRO • 2023 • PubMed indexed study
PMID 37496410 from Iranian journal of allergy, asthma, and immunology.
Outcome: Study design: IN_VITRO. Quality score: 2.8/10.[1471,1516,1519, etc.]
Open source 96. Effects of astragaloside IV on the proliferation and osteogenic differentiation of human jaw bone marrow mesenchymal stem cells in vitro.
IN_VITRO • 2026 • PubMed indexed study
PMID 40817916 from Naunyn-Schmiedeberg's archives of pharmacology.
Outcome: Study design: IN_VITRO. Quality score: 2.8/10.[1471,1516,1519, etc.]