Habit
Reduce and ideally discontinue e-cigarette nicotine exposure.[2574,2744,2886, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 0 • links 35
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Classification: reduce.[1145,1303,2574, etc.]
Best fit: Current vape users, especially dual users with smoking..[1145,1303,2574, etc.]
Goal alignment: Heart Health, Longevity, Performance, Sleep.[1145,1303,2574, etc.]
Classification
Reduce
Evidence Tier
HIGH
Best Fit
Current vape users, especially dual users with smoking.
Primary Focus
Heart Health, Longevity
Clinical Depth
Humans: 2,762 • RCTs: 188 • Meta: 33
Cohort / Real-World
Cohort signals: 356
Safety Markers
Adverse signals: 611 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
2762 total studies · 11 recent
Timeline
Total indexed
2,762
Human studies
2,762
Safety adverse signals
611
Dependency signals
365
Cohort signals
356
In vitro / tissue
267
Weighted direction score: 0 (Mixed / Neutral)
High when replicated human meta-analysis/trial/cohort depth is present for the habit or exposure.
Total indexed
2,762
Human studies
2,762
Safety adverse signals
611
Dependency signals
365
Cohort signals
356
In vitro / tissue
267
Cardiometabolic signals
210
Randomized trials
188
Neuropsych signals
165
Sleep signals
38
Meta-analyses
33
Distribution of evidence by study design strength
Evidence Strength: High
PMID 38030217 • 2023 Nov 29
Social media use and health risk behaviours in young people: systematic review and meta-analysis.
BMJ (Clinical research ed.)
Open PubMedPMID 40010935 • 2025 Jun 13
Cardiovascular health effects of vaping e-cigarettes: a systematic review and meta-analysis.
Heart (British Cardiac Society)
Open PubMedPMID 39754882 • 2025 Mar 15
Associations between vaping during pregnancy and perinatal outcomes: A systematic review and meta-analysis.
Journal of hazardous materials
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22vaping%20nicotine%22%20(exercise%20OR%20training%20OR%20sleep%20OR%20habit%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3AFitness%20OR%20subreddit%3Abodyweightfitness%20OR%20subreddit%3Aweightroom%20OR%20subreddit%3Arunning%20OR%20subreddit%3ACycling%20OR%20subreddit%3Aswimming%20OR%20subreddit%3AHIIT%20OR%20subreddit%3Ayoga%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3Ameditation%20OR%20subreddit%3Asleep%20OR%20subreddit%3Astopsmoking%20OR%20subreddit%3Astopdrinking%20OR%20subreddit%3Aleaves%20OR%20subreddit%3Adecaf%20OR%20subreddit%3Adecidingtobebetter)
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Human lifestyle/habit literature
Counts from structured habit/exposure PubMed query set.
Outcome: Humans 2754, RCT 188, meta 33, cohort 354, sleep signals 38, cardiometabolic signals 207.[2574,2744,2886, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 38030217 from BMJ (Clinical research ed.).
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Animal-only studies
0
Composite of study volume, RCTs, and meta-analyses
PMID 40651293 • 2025 Sep
Maternal vaping and pregnancy adverse outcomes: A systematic review and meta-analysis.
Women and birth : journal of the Australian College of Midwives
Open PubMedPMID 40892018 • 2025 Dec
Vaping and Smoking in Pregnancy-A Meta-Analysis of Neurobehavioural Development in Prenatally Exposed Offspring.
Acta paediatrica (Oslo, Norway : 1992)
Open PubMedPMID 36882378 • 2023 Jul
Do Vaping Prevention Messages Impact Adolescents and Young Adults? A Meta-Analysis of Experimental Studies.
Health communication
Open PubMedPMID 36426864 • 2023 Apr 6
Exposure to Electronic Cigarette Advertisements and Use of Electronic Cigarettes: A Meta-analysis of Prospective Studies.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Open PubMedPMID 39129583 • 2024 Dec
The relationship between cannabis and nicotine use: A systematic review and meta-analysis.
Addiction (Abingdon, England)
Open PubMedPMID 39604914 • 2024 Nov 28
A global prevalence of electronic nicotine delivery systems (ENDS) use among students: a systematic review and meta-analysis of 4,189,145 subjects.
BMC public health
Open PubMedPMID 39826373 • 2025 Apr
Evidence update on e-cigarette dependence: A systematic review and meta-analysis.
Addictive behaviors
Open PubMedPMID 41133437 • 2026 Jan
Smoking and Risk of Uveitis: A Systematic Review and Meta-Analysis.
Ocular immunology and inflammation
Open PubMedPMID 38783343 • 2024 Sep
The impact of exposure to tobacco smoke and e-cigarettes on asthma-related outcomes: Systematic review informing the EAACI guidelines on environmental science for allergic diseases and asthma.
Allergy
Open PubMedPMID 37619211 • 2024 Feb 22
Exposure to Tobacco-Specific Nitrosamines Among People Who Vape, Smoke, or do Neither: A Systematic Review and Meta-Analysis.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Open PubMedPMID 38618685 • 2024 Sep 23
The Effect of Nicotine-Containing Products on Peri-Implant Tissues: A Systematic Review and Network Meta-Analysis.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Open PubMedPMID 37088177 • 2023 Sep
Association of Electronic Cigarette Exposure on Cardiovascular Health: A Systematic Review and Meta-Analysis.
Current problems in cardiology
Open PubMedPMID 31641752 • 2020 Jun 12
Human Biomarker Exposure From Cigarettes Versus Novel Heat-Not-Burn Devices: A Systematic Review and Meta-Analysis.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco
Open PubMedPMID 34808583 • 2021 Dec
Immediate physiological effects of acute electronic cigarette use in humans: A systematic review and meta-analysis.
Respiratory medicine
Open PubMedPMID 30012646 • 2018 Jul 16
E-cigarette adverts and children's perceptions of tobacco smoking harms: an experimental study and meta-analysis.
BMJ open
Open PubMedPMID 35816331 • 2022 Sep 1
Association Between Exposure to Tobacco Content on Social Media and Tobacco Use: A Systematic Review and Meta-analysis.
JAMA pediatrics
Open PubMedPMID 26776875 • 2016 Feb
E-cigarettes and smoking cessation in real-world and clinical settings: a systematic review and meta-analysis.
The Lancet. Respiratory medicine
Open PubMedPMID 35502561 • 2022 Dec
Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis.
Health education & behavior : the official publication of the Society for Public Health Education
Open PubMedPMID 35556173 • 2022 Jul
Evaluation of periodontal indices among non-smokers, tobacco, and e-cigarette smokers: a systematic review and network meta-analysis.
Clinical oral investigations
Open PubMedPMID 34078351 • 2021 Jun 3
Association between electronic cigarette use and tobacco cigarette smoking initiation in adolescents: a systematic review and meta-analysis.
BMC public health
Open PubMedPMID 28379177 • 2017 Apr 5
A Comparative Health Risk Assessment of Electronic Cigarettes and Conventional Cigarettes.
International journal of environmental research and public health
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=vaping%20nicotine
Community Sources
PUBMED • 2025 • Human evidence curation set
PMID 40010935 from Heart (British Cardiac Society).
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 39754882 from Journal of hazardous materials.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40651293 from Women and birth : journal of the Australian College of Midwives.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40892018 from Acta paediatrica (Oslo, Norway : 1992).
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36882378 from Health communication.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36426864 from Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39129583 from Addiction (Abingdon, England).
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39604914 from BMC public health.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 39826373 from Addictive behaviors.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2026 • Human evidence curation set
PMID 41133437 from Ocular immunology and inflammation.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38783343 from Allergy.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 37619211 from Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38618685 from Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37088177 from Current problems in cardiology.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31641752 from Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34808583 from Respiratory medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30012646 from BMJ open.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35816331 from JAMA pediatrics.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 26776875 from The Lancet. Respiratory medicine.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35502561 from Health education & behavior : the official publication of the Society for Public Health Education.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35556173 from Clinical oral investigations.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34078351 from BMC public health.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28379177 from International journal of environmental research and public health.
Outcome: See linked PubMed abstract for methods and outcomes.[2574,2744,2886, etc.]
Open source