Food
Curcuminoids from turmeric are linked to inflammatory-signaling modulation.[2869,3352,3568, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: prioritize.[1142,1299,2869, etc.]
Best fit: Users with high inflammatory load or joint discomfort patterns..[1142,1299,2869, etc.]
Goal alignment: Recovery, Joint Health, Metabolic Health.[1142,1299,2869, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users with high inflammatory load or joint discomfort patterns.
Primary Focus
Recovery, Joint Health
Clinical Depth
Humans: 1,893 • RCTs: 129 • Meta: 37
Cohort / Real-World
Cohort signals: 52
Safety Markers
Adverse signals: 286 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
1893 total studies · 5 recent
Timeline
In vitro / tissue
4,141
Total indexed
1,893
Human studies
1,893
Safety adverse signals
286
Randomized trials
129
Cohort signals
52
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
In vitro / tissue
4,141
Total indexed
1,893
Human studies
1,893
Safety adverse signals
286
Randomized trials
129
Cohort signals
52
Meta-analyses
37
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 33762150 • 2021 May 6
The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.
Nutr Metab Cardiovasc Dis
Open PubMedPMID 29018060 • 2018 Feb
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Br J Sports Med
Open PubMedPMID 35458170 • 2022 Apr 12
A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms.
Nutrients
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
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aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 1893, RCT 129, meta 37, cohort 52.[2869,3352,3568, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33762150 from Nutr Metab Cardiovasc Dis.
Outcome: See linked PubMed abstract for methods and outcomes.
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
PMID 36940841 • 2023 Jun
Non-pharmacological interventions in the treatment of rheumatoid arthritis: A systematic review and meta-analysis.
Autoimmun Rev
Open PubMedPMID 37522129 • 2023
Effects of dietary polyphenol curcumin supplementation on metabolic, inflammatory, and oxidative stress indices in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials.
Front Endocrinol (Lausanne)
Open PubMedPMID 36159792 • 2022
Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Front Immunol
Open PubMedPMID 36192751 • 2022 Oct 3
Effects of curcumin and/or coenzyme Q10 supplementation on metabolic control in subjects with metabolic syndrome: a randomized clinical trial.
Nutr J
Open PubMedPMID 38794742 • 2024 May 16
Effects of Mediterranean Diet, Curcumin, and Resveratrol on Mild-to-Moderate Active Ulcerative Colitis: A Multicenter Randomized Clinical Trial.
Nutrients
Open PubMedPMID 38795741 • 2024 Jul
Curcumin supplementation alleviates hepatic fat content associated with modulation of gut microbiota-dependent bile acid metabolism in patients with nonalcoholic simple fatty liver disease: a randomized controlled trial.
Am J Clin Nutr
Open PubMedPMID 32180294 • 2020 Aug
Herbal formulation "turmeric extract, black pepper, and ginger" versus Naproxen for chronic knee osteoarthritis: A randomized, double-blind, controlled clinical trial.
Phytother Res
Open PubMedPMID 40266024 • 2025 Apr 17
Dietary associations with reduced epigenetic age: a secondary data analysis of the methylation diet and lifestyle study.
Aging (Albany NY)
Open PubMedPMID 35150143 • 2022 May
Does nano-curcumin supplementation improve hematological indices in critically ill patients with sepsis? A randomized controlled clinical trial.
J Food Biochem
Open PubMedPMID 39102266 • 2024 Aug 1
Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults.
JAMA Netw Open
Open PubMedPMID 40198579 • 2025 Apr
Food additive mixtures and type 2 diabetes incidence: Results from the NutriNet-Santé prospective cohort.
PLoS Med
Open PubMedPMID 31329006 • 2019 Nov
Dietary Management of Pediatric Inflammatory Bowel Disease.
J Med Food
Open PubMedPMID 36868489 • 2023 Jul
The Evolving Profile of Idiosyncratic Drug-Induced Liver Injury.
Clin Gastroenterol Hepatol
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=turmeric%20as%20culinary%20spice
Community Sources
PUBMED • 2018 • Human evidence curation set
PMID 29018060 from Br J Sports Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35458170 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36940841 from Autoimmun Rev.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37522129 from Front Endocrinol (Lausanne).
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36159792 from Front Immunol.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36192751 from Nutr J.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38794742 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38795741 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32180294 from Phytother Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40266024 from Aging (Albany NY).
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35150143 from J Food Biochem.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39102266 from JAMA Netw Open.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40198579 from PLoS Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31329006 from J Med Food.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36868489 from Clin Gastroenterol Hepatol.
Outcome: See linked PubMed abstract for methods and outcomes.[2869,3352,3568, etc.]
Open source