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Food

Seaweed

Provides iodine and unique marine polysaccharides that may support thyroid and metabolic pathways.[3126,3249,3750, etc.]

Superscript reference numbers link to the Sources bibliography.

Strong Evidence
Hormone HealthMetabolic HealthImmune Support

Composite Rating

3.9/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

100/100

High depth from human/RCT/meta counts

Community Direction

0

Mixed / Neutral • confidence Minimal

Safety Friction

82/100

High signal from adverse/interaction markers

Data Completeness

100%

Studies 16 • mentions 0 • links 25

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Classification: prioritize.[1124,1271,3126, etc.]

Best fit: Users with low marine food intake and low iodine status risk..[1124,1271,3126, etc.]

Goal alignment: Hormone Health, Metabolic Health, Immune Support.[1124,1271,3126, etc.]

Classification

Prioritize

Evidence Tier

HIGH

Best Fit

Users with low marine food intake and low iodine status risk.

Primary Focus

Hormone Health, Metabolic Health

Safety and Pitfalls

  • Excess iodine from concentrated products may worsen thyroid disorders.

At-A-Glance Evidence Architecture[3126,3249,3750, etc.]

Clinical Depth

Humans: 746 • RCTs: 36 • Meta: 7

Cohort / Real-World

Cohort signals: 65

Safety Markers

Adverse signals: 67 • Interactions: 0

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

New Evidence

Trend

→ Stable evidence base

Depth

746 total studies · 4 recent

Timeline

20182025

Top Signal Metrics[3126,3249,3750, etc.]

Total indexed

746

Human studies

746

In vitro / tissue

458

Safety adverse signals

67

Cohort signals

65

Randomized trials

36

Community Direction Mix[1124,1271,6372]

Weighted direction score: 0 (Mixed / Neutral)

Benefit

Evidence Quality Summary[3126,3249,3750, etc.]

High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.

Total indexed

746

Human studies

746

In vitro / tissue

458

Safety adverse signals

67

Cohort signals

65

Randomized trials

36

Meta-analyses

7

Animal-only studies

0

Study Type Breakdown

Distribution of evidence by study design strength

Meta-AnalysesLevel 1a7
Randomized TrialsLevel 1b36
Cohort StudiesLevel 2b65
Human Studies (other)Level 3-4638
All IndexedAll levels746
100

Evidence Strength: High

Top Human Studies[3126,3249,3750, etc.]

PMID 38068845 • 2023 Dec 1

Brown Seaweed Consumption as a Promising Strategy for Blood Glucose Management: A Comprehensive Meta-Analysis.

Nutrients

Open PubMed

PMID 40726022 • 2025 Aug

Edible Algae Reduce Blood Pressure in Humans: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

J Hum Nutr Diet

Open PubMed

PMID 37103359 • 2023 Mar 30

How Do Brown Seaweeds Work on Biomarkers of Dyslipidemia? A Systematic Review with Meta-Analysis and Meta-Regression.

Mar Drugs

Open PubMed

Community Report Frequency[1124,1271,6372]

Benefit reports: 0

Adverse reports: 0

No-effect reports: 0

Mixed reports: 0

Unclear reports: 0

Signal confidence: 0.00

Top Reported Effects[1124,1271,6372]

Benefits

  • Hormone Health: 1
  • Metabolic Health: 1
  • Immune Support: 1

Adverse

  • Excess iodine from concentrated products may worsen thyroid disorders: 1

No Effect

  • insufficient no-effect reports captured: 0

Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.

Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22seaweed%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)

Community Evidence Examples[1124,1271,6372]

aggregate • unclear

No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.

Open mention

Primary Source Links

Evidence Sources

  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22seaweed%22%20OR%20%22edible%20algae%22%20AND%20humans%5BMeSH%20Terms%5D)%20AND%20(diet*%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20consumption%5BTitle%2FAbstract%5D%20OR%20feeding%5BTitle%2FAbstract%5D%20OR%20nutrition%5BTitle%2FAbstract%5D)
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22seaweed%22%20OR%20%22edible%20algae%22%20AND%20humans%5BMeSH%20Terms%5D)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(diet*%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20consumption%5BTitle%2FAbstract%5D%20OR%20feeding%5BTitle%2FAbstract%5D%20OR%20nutrition%5BTitle%2FAbstract%5D)
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22seaweed%22%20OR%20%22edible%20algae%22%20AND%20humans%5BMeSH%20Terms%5D)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(diet*%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20consumption%5BTitle%2FAbstract%5D%20OR%20feeding%5BTitle%2FAbstract%5D%20OR%20nutrition%5BTitle%2FAbstract%5D)%20AND%20randomized%20controlled%20trial%5BPublication%20Type%5D

Scientific Evidence Notes[3126,3249,3750, etc.]

1. PubMed triage evidence summary: Seaweed

PUBMED • Humans + preclinical triage

Counts from structured PubMed query set for diet/intake context.

Outcome: Humans 746, RCT 36, meta 7, cohort 65.[3126,3249,3750, etc.]

Open source
2. Brown Seaweed Consumption as a Promising Strategy for Blood Glucose Management: A Comprehensive Meta-Analysis.

PUBMED • 2023 • Human evidence curation set

PMID 38068845 from Nutrients.

Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]

[1124,1271,3126, etc.]
0
Adverse0
No Effect0
Mixed0

No directional mention volume was resolved; fallback profile metadata is shown in other sections.

Composite of study volume, RCTs, and meta-analyses

PMID 35233943 • 2022 Mar

Iodine from brown algae in human nutrition, with an emphasis on bioaccessibility, bioavailability, chemistry, and effects of processing: A systematic review.

Compr Rev Food Sci Food Saf

Open PubMed

PMID 34967190 • 2021 Dec

Effects of resistant starch supplementation on oxidative stress and inflammation biomarkers: A systematic review and meta-analysis of randomized controlled trials.

Asia Pac J Clin Nutr

Open PubMed

PMID 39728103 • 2024 Nov 25

Anti-Obesity Effects of Sulphated Polysaccharides Derived from Marine Macro Algae or Seaweeds: A Systematic Review and Meta-Analysis.

Mar Drugs

Open PubMed

PMID 38608850 • 2024 Jun

The bioaccessibility and tolerability of marine-derived sources of magnesium and calcium.

Methods

Open PubMed

PMID 38931192 • 2024 Jun 12

The Effect of Sargassum fusiforme and Fucus vesiculosus on Continuous Glucose Levels in Overweight Patients with Type 2 Diabetes Mellitus: A Feasibility Randomized, Double-Blind, Placebo-Controlled Trial.

Nutrients

Open PubMed

PMID 37344446 • 2023 Dec 1

Effects of Nutrition Education Program for the Japan Diet on Serum Phospholipid Fatty Acid Compositions in Patients with Dyslipidemia: Re-analysis of Data from a Previous Randomized Controlled Trial.

J Atheroscler Thromb

Open PubMed

PMID 36746392 • 2023 Oct 28

A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men.

Br J Nutr

Open PubMed

PMID 35323474 • 2022 Feb 26

Marginal Impact of Brown Seaweed Ascophyllum nodosum and Fucus vesiculosus Extract on Metabolic and Inflammatory Response in Overweight and Obese Prediabetic Subjects.

Mar Drugs

Open PubMed

PMID 30321272 • 2018 Oct 1

Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial.

Am J Clin Nutr

Open PubMed

PMID 32908248 • 2021 Jun

Impact of seaweed intake on health.

Eur J Clin Nutr

Open PubMed

PMID 30840077 • 2019 May 1

Risks and benefits of consuming edible seaweeds.

Nutr Rev

Open PubMed

PMID 37038991 • 2023 Sep 1

Seaweed consumption and the risk of prostate cancer: the Miyagi cohort study.

Eur J Cancer Prev

Open PubMed

PMID 35607818 • 2022 Jun

Seaweed and Iodine Intakes and SLC5A5 rs77277498 in Relation to Thyroid Cancer.

Endocrinol Metab (Seoul)

Open PubMed

Fallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=seaweed

  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22seaweed%22%20OR%20%22edible%20algae%22%20AND%20humans%5BMeSH%20Terms%5D)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(diet*%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20consumption%5BTitle%2FAbstract%5D%20OR%20feeding%5BTitle%2FAbstract%5D%20OR%20nutrition%5BTitle%2FAbstract%5D)%20AND%20meta-analysis%5BPublication%20Type%5D
  • https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=(%22seaweed%22%20OR%20%22edible%20algae%22%20AND%20humans%5BMeSH%20Terms%5D)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(diet*%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20consumption%5BTitle%2FAbstract%5D%20OR%20feeding%5BTitle%2FAbstract%5D%20OR%20nutrition%5BTitle%2FAbstract%5D)%20AND%20(cohort%5BTitle%2FAbstract%5D%20OR%20prospective%5BTitle%2FAbstract%5D%20OR%20longitudinal%5BTitle%2FAbstract%5D)
  • https://pubmed.ncbi.nlm.nih.gov/38068845/
  • https://pubmed.ncbi.nlm.nih.gov/40726022/
  • https://pubmed.ncbi.nlm.nih.gov/37103359/
  • https://pubmed.ncbi.nlm.nih.gov/35233943/
  • https://pubmed.ncbi.nlm.nih.gov/34967190/
  • https://pubmed.ncbi.nlm.nih.gov/39728103/
  • https://pubmed.ncbi.nlm.nih.gov/38608850/
  • https://pubmed.ncbi.nlm.nih.gov/38931192/
  • https://pubmed.ncbi.nlm.nih.gov/37344446/
  • https://pubmed.ncbi.nlm.nih.gov/36746392/
  • https://pubmed.ncbi.nlm.nih.gov/35323474/
  • https://pubmed.ncbi.nlm.nih.gov/30321272/
  • https://pubmed.ncbi.nlm.nih.gov/32908248/
  • https://pubmed.ncbi.nlm.nih.gov/30840077/
  • https://pubmed.ncbi.nlm.nih.gov/37038991/
  • Community Sources

    • https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22seaweed%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
    • https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=seaweed
    • https://www.reddit.com/search/?q=Seaweed
    3126,
    3249,
    3750
    Open source
    3. Edible Algae Reduce Blood Pressure in Humans: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.

    PUBMED • 2025 • Human evidence curation set

    PMID 40726022 from J Hum Nutr Diet.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    4. How Do Brown Seaweeds Work on Biomarkers of Dyslipidemia? A Systematic Review with Meta-Analysis and Meta-Regression.

    PUBMED • 2023 • Human evidence curation set

    PMID 37103359 from Mar Drugs.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    5. Iodine from brown algae in human nutrition, with an emphasis on bioaccessibility, bioavailability, chemistry, and effects of processing: A systematic review.

    PUBMED • 2022 • Human evidence curation set

    PMID 35233943 from Compr Rev Food Sci Food Saf.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    6. Effects of resistant starch supplementation on oxidative stress and inflammation biomarkers: A systematic review and meta-analysis of randomized controlled trials.

    PUBMED • 2021 • Human evidence curation set

    PMID 34967190 from Asia Pac J Clin Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    7. Anti-Obesity Effects of Sulphated Polysaccharides Derived from Marine Macro Algae or Seaweeds: A Systematic Review and Meta-Analysis.

    PUBMED • 2024 • Human evidence curation set

    PMID 39728103 from Mar Drugs.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    8. The bioaccessibility and tolerability of marine-derived sources of magnesium and calcium.

    PUBMED • 2024 • Human evidence curation set

    PMID 38608850 from Methods.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    9. The Effect of Sargassum fusiforme and Fucus vesiculosus on Continuous Glucose Levels in Overweight Patients with Type 2 Diabetes Mellitus: A Feasibility Randomized, Double-Blind, Placebo-Controlled Trial.

    PUBMED • 2024 • Human evidence curation set

    PMID 38931192 from Nutrients.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    10. Effects of Nutrition Education Program for the Japan Diet on Serum Phospholipid Fatty Acid Compositions in Patients with Dyslipidemia: Re-analysis of Data from a Previous Randomized Controlled Trial.

    PUBMED • 2023 • Human evidence curation set

    PMID 37344446 from J Atheroscler Thromb.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    11. A comparative, randomised MRI study of the physiological and appetitive responses to gelling (alginate) and non-gelling nasogastric tube feeds in healthy men.

    PUBMED • 2023 • Human evidence curation set

    PMID 36746392 from Br J Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    12. Marginal Impact of Brown Seaweed Ascophyllum nodosum and Fucus vesiculosus Extract on Metabolic and Inflammatory Response in Overweight and Obese Prediabetic Subjects.

    PUBMED • 2022 • Human evidence curation set

    PMID 35323474 from Mar Drugs.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    13. Impact of a (poly)phenol-rich extract from the brown algae Ascophyllum nodosum on DNA damage and antioxidant activity in an overweight or obese population: a randomized controlled trial.

    PUBMED • 2018 • Human evidence curation set

    PMID 30321272 from Am J Clin Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    14. Impact of seaweed intake on health.

    PUBMED • 2021 • Human evidence curation set

    PMID 32908248 from Eur J Clin Nutr.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    15. Risks and benefits of consuming edible seaweeds.

    PUBMED • 2019 • Human evidence curation set

    PMID 30840077 from Nutr Rev.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    16. Seaweed consumption and the risk of prostate cancer: the Miyagi cohort study.

    PUBMED • 2023 • Human evidence curation set

    PMID 37038991 from Eur J Cancer Prev.

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source
    17. Seaweed and Iodine Intakes and SLC5A5 rs77277498 in Relation to Thyroid Cancer.

    PUBMED • 2022 • Human evidence curation set

    PMID 35607818 from Endocrinol Metab (Seoul).

    Outcome: See linked PubMed abstract for methods and outcomes.[3126,3249,3750, etc.]

    Open source