Food
Ellagitannin-rich profile may support endothelial and oxidative-stress markers.[2366,2962,3205, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
100
Positive Lean • confidence Moderate
Safety Friction
41/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 8 • links 25
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Classification: prioritize.[424,1258,2366, etc.]
Best fit: Users focused on vascular health and produce diversity..[424,1258,2366, etc.]
Goal alignment: Heart Health, Metabolic Health, Longevity.[424,1258,2366, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users focused on vascular health and produce diversity.
Primary Focus
Heart Health, Metabolic Health
Clinical Depth
Humans: 160 • RCTs: 80 • Meta: 24
Cohort / Real-World
Cohort signals: 4
Safety Markers
Adverse signals: 7 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
257 total studies · 2 recent
Timeline
Total indexed
257
Human studies
160
Randomized trials
80
Animal-only studies
77
In vitro / tissue
74
Meta-analyses
24
Weighted direction score: 100 (Positive Lean)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
257
Human studies
160
Randomized trials
80
Animal-only studies
77
In vitro / tissue
74
Meta-analyses
24
Safety adverse signals
7
Cohort signals
4
Distribution of evidence by study design strength
Evidence Strength: High
PMID 36940841 • 2023 Jun
Non-pharmacological interventions in the treatment of rheumatoid arthritis: A systematic review and meta-analysis.
Autoimmun Rev
Open PubMedPMID 34965876 • 2021 Dec 29
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials.
J Int Soc Sports Nutr
Open PubMedPMID 37033930 • 2023
Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials.
Benefit reports: 2
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 6
Signal confidence: 0.47
Benefits
Adverse
No Effect
Community confidence 0.47 with mentions: benefit 2, adverse 0, no-effect 0.
Subreddit coverage: Biohackers, mediterraneandiet, nutrition.
post • r/mediterraneandiet • unclear
This was perfect! Kale Salad with Sweet Potatoes and Pomegranate Vinaigrette from The Complete Mediterranean Cookbook by America’s Test Kitchen I loved this salad! So flavorful and it left me feeling satisfied. Recipe is second picture. Hi…
Open mentionpost • r/nutrition • unclear
Is my diet bad? I eat the same thing every week. **Not trying to be “overly healthy,” but curious if I’m missing anything long-term** I’m not aiming for a perfect diet, but I’m wondering if there’s anything obvious I might be missing that …
Open mentionpost • r/Biohackers • benefit
The ONLY things that actually improved my IBS after years of trying everything I tried all the mainstream recommendations: low FODMAP, probiotics, enzymes, fasting, fiber experiments… Nothing gave me a real breakthrough. The ONLY things th…
Evidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 160, RCT 80, meta 24, cohort 4.[2366,2962,3205, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36940841 from Autoimmun Rev.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
Composite of study volume, RCTs, and meta-analyses
Front Immunol
PMID 29518971 • 2018 Mar 7
Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms.
Int J Mol Sci
Open PubMedPMID 35063191 • 2022 Feb
Does pomegranate consumption improve oxidative stress? A systematic review and meta-analysis of randomized controlled clinical trials.
Clin Nutr ESPEN
Open PubMedPMID 37507609 • 2023 Oct
The effects of pomegranate consumption on inflammatory and oxidative stress biomarkers in adults: a systematic review and meta-analysis.
Inflammopharmacology
Open PubMedPMID 38887904 • 2024 Jul 3
Pomegranate Juice Supplemented with Inulin Modulates Gut Microbiota and Promotes the Production of Microbiota-Associated Metabolites in Overweight/Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial.
J Agric Food Chem
Open PubMedPMID 34288973 • 2021
Influence of a new botanical combination on quality of life in menopausal Spanish women: Results of a randomized, placebo-controlled pilot study.
PLoS One
Open PubMedPMID 30661697 • 2019 Feb
Effects of pomegranate juice consumption on blood pressure and lipid profile in patients with type 2 diabetes: A single-blind randomized clinical trial.
Clin Nutr ESPEN
Open PubMedPMID 36505757 • 2022
The Effect of Pomegranate Juice and Sumac Consumption in the Treatment of Outpatients with COVID-19.
Mediators Inflamm
Open PubMedPMID 31711104 • 2020 Jan 1
Randomized placebo-controlled study of the memory effects of pomegranate juice in middle-aged and older adults.
Am J Clin Nutr
Open PubMedPMID 39608758 • 2025 Feb
Effect of Pomegranate Peel Consumption on Liver Enzymes, Lipid Profile, Liver Steatosis, and Hs-CRP in Patients With Non-alcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Phytother Res
Open PubMedPMID 33574371 • 2021 Feb 11
A randomized controlled trial investigating the impact of maternal dietary supplementation with pomegranate juice on brain injury in infants with IUGR.
Sci Rep
Open PubMedPMID 25275520 • 2014
An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial.
PLoS One
Open PubMedPMID 32425160 • 2020 Jan
Longitudinal assessment of carotid plaque texture in three-dimensional ultrasound images based on semi-supervised graph-based dimensionality reduction and feature selection.
Comput Biol Med
Open PubMedPMID 31577095 • 2019 Oct 2
Nutraceutical treatment and prevention of benign prostatic hyperplasia and prostate cancer.
Arch Ital Urol Androl
Open PubMedpost • r/nutrition • unclear
What fruits are actually worth eating? So I don't really like eating fruits but I know I they are still essential for micronutrients. I'm trying to figure out what is the minimum variety of fruits I can eat without compromising my nutritio…
Open mentionpost • r/mediterraneandiet • benefit
Winner winner Mediterranean diet dinner No recipe, just stuff: Roasted sweet potato (375 for 2-3 hours? I forgot about them) Roasted orange and yellow peppers A schmear of Toum (bought the premade toom brand) Pomegranate seeds Lots of cila…
Open mentionpost • r/Biohackers • unclear
Increased Testosterone from 205 to 528 in 8 weeks Age: 33 Male Vitamin D: 23.8 >>> 31.5 Testosterone: 205 >>> 528 In addition to this, started working out daily including strength training with weights and running on treadmill and cycling …
Open mentioncomment • r/mediterraneandiet • unclear
Looks so good! Where did you buy the pomegranate molasses? Everything on Amazon is $12+
Open mentioncomment • r/mediterraneandiet • unclear
You can make your own! From this cookbook: simmer 2 cups pomegranate juice, 1 tablespoon brown sugar and a pinch of salt until syrup consistency. Or substitute a fruity, tart jam, like Lingonberry, since the dressing for this recipe calls …
Open mentionCommunity Sources
PUBMED • 2021 • Human evidence curation set
PMID 34965876 from J Int Soc Sports Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37033930 from Front Immunol.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29518971 from Int J Mol Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35063191 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37507609 from Inflammopharmacology.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38887904 from J Agric Food Chem.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34288973 from PLoS One.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30661697 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36505757 from Mediators Inflamm.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 31711104 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 39608758 from Phytother Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33574371 from Sci Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 25275520 from PLoS One.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32425160 from Comput Biol Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31577095 from Arch Ital Urol Androl.
Outcome: See linked PubMed abstract for methods and outcomes.[2366,2962,3205, etc.]
Open source