Food
Persistent chemicals in certain food-contact pathways are associated with multi-system risk signals.[2938,3178,3201, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
91/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
56/100
Moderate signal from adverse/interaction markers
Data Completeness
100%
Studies 15 • mentions 0 • links 24
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Classification: limit.[1053,1158,2938, etc.]
Best fit: Users minimizing long-term contaminant burden..[1053,1158,2938, etc.]
Goal alignment: Hormone Health, Liver Support, Immune Support.[1053,1158,2938, etc.]
Classification
Limit
Evidence Tier
HIGH
Best Fit
Users minimizing long-term contaminant burden.
Primary Focus
Hormone Health, Liver Support
Clinical Depth
Humans: 133 • RCTs: 3 • Meta: 1
Cohort / Real-World
Cohort signals: 38
Safety Markers
Adverse signals: 17 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
133 total studies · 7 recent
Timeline
Total indexed
133
Human studies
133
Cohort signals
38
Safety adverse signals
17
In vitro / tissue
7
Randomized trials
3
Weighted direction score: 0 (Mixed / Neutral)
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
133
Human studies
133
Cohort signals
38
Safety adverse signals
17
In vitro / tissue
7
Randomized trials
3
Meta-analyses
1
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 30544905 • 2018 Dec 11
Socio-Economic Status and Health: Evaluation of Human Biomonitored Chemical Exposure to Per- and Polyfluorinated Substances across Status.
Int J Environ Res Public Health
Open PubMedPMID 30646133 • 2018 Aug 3
Association of Perfluoroalkyl and Polyfluoroalkyl Substances With Adiposity.
JAMA Netw Open
Open PubMedPMID 37011795 • 2023 Jul 1
Predictors of serum- per- and polyfluoroalkyl substance (PFAS) concentrations among infants in Guinea-Bissau, West Africa.
Environ Res
Open PubMedPMID 29438414 • 2018 Feb
Perfluoroalkyl substances and changes in body weight and resting metabolic rate in response to weight-loss diets: A prospective study.
PLoS Med
Open PubMedPMID 40845633 • 2025 Sep 15
Xenobiotic-induced liver injury: Molecular mechanisms and disease progression.
Ecotoxicol Environ Saf
Open PubMedPMID 40889412 • 2025 Sep
Metabolome informs about the chemical exposome and links to brain health.
Environ Int
Open PubMedPMID 36509187 • 2023 Feb
PFAS levels and exposure determinants in sensitive population groups.
Chemosphere
Open PubMedPMID 39304148 • 2024 Dec 1
Cross-cutting studies of per- and polyfluorinated alkyl substances (PFAS) in Arctic wildlife and humans.
Sci Total Environ
Open PubMedPMID 38316574 • 2024 Mar
Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study.
Environ Int
Open PubMedPMID 39485370 • 2024 Nov 12
Mid-Childhood Plasma Concentrations of Per- and Polyfluoroalkyl Substances, Modifiable Lifestyle Factors, and Bone Mineral Density Through Late Adolescence.
Environ Sci Technol
Open PubMedPMID 31421451 • 2019 Oct
Human exposure to per- and polyfluoroalkyl substances (PFAS) through drinking water: A review of the recent scientific literature.
Environ Res
Open PubMedPMID 40365998 • 2025 May 27
Exposure to Legacy Per- and Polyfluoroalkyl Substances from Diet and Drinking Water in California Adults, 2018-2020.
Environ Sci Technol
Open PubMedPMID 37844865 • 2023 Dec 15
Inflammation and cardiometabolic diseases induced by persistent organic pollutants and nutritional interventions: Effects of multi-organ interactions.
Environ Pollut
Open PubMedPMID 39383969 • 2024 Dec 1
Effects of per- and polyfluoroalkyl substances on the liver: Human-relevant mechanisms of toxicity.
Sci Total Environ
Open PubMedPMID 36327670 • 2023 Jan
PFAS levels and determinants of variability in exposure in European teenagers - Results from the HBM4EU aligned studies (2014-2021).
Int J Hyg Environ Health
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22PFAS%20food%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
Fallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=PFAS%20food
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
Community Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 133, RCT 3, meta 1, cohort 38.[2938,3178,3201, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30544905 from Int J Environ Res Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30646133 from JAMA Netw Open.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37011795 from Environ Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29438414 from PLoS Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40845633 from Ecotoxicol Environ Saf.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40889412 from Environ Int.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36509187 from Chemosphere.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39304148 from Sci Total Environ.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38316574 from Environ Int.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39485370 from Environ Sci Technol.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31421451 from Environ Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40365998 from Environ Sci Technol.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37844865 from Environ Pollut.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39383969 from Sci Total Environ.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36327670 from Int J Hyg Environ Health.
Outcome: See linked PubMed abstract for methods and outcomes.[2938,3178,3201, etc.]
Open source