Food
Micronutrient-dense source of vitamin A, B12, folate, copper, and iron.[1941,2313,2861, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Classification: case-dependent.[1057,1165,1941, etc.]
Best fit: Users with low micronutrient status and no vitamin A contraindication..[1057,1165,1941, etc.]
Goal alignment: Energy, Skin Hair, Hormone Health.[1057,1165,1941, etc.]
Classification
Case Dependent
Evidence Tier
HIGH
Best Fit
Users with low micronutrient status and no vitamin A contraindication.
Primary Focus
Energy, Skin Hair
Clinical Depth
Humans: 13,253 • RCTs: 969 • Meta: 187
Cohort / Real-World
Cohort signals: 1,058
Safety Markers
Adverse signals: 1,195 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
13253 total studies · 5 recent
Timeline
Total indexed
13,253
Human studies
13,253
In vitro / tissue
3,751
Safety adverse signals
1,195
Cohort signals
1,058
Randomized trials
969
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
13,253
Human studies
13,253
In vitro / tissue
3,751
Safety adverse signals
1,195
Cohort signals
1,058
Randomized trials
969
Meta-analyses
187
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 40533200 • 2025 Jun 18
Intermittent fasting strategies and their effects on body weight and other cardiometabolic risk factors: systematic review and network meta-analysis of randomised clinical trials.
BMJ
Open PubMedPMID 34187442 • 2021 Jun 29
The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials.
BMC Complement Med Ther
Open PubMedPMID 35285920 • 2022 Mar 1
Benefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22beef%20liver%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 13253, RCT 969, meta 187, cohort 1058.[1941,2313,2861, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40533200 from BMJ.
Outcome: See linked PubMed abstract for methods and outcomes.
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
Association of Low- and No-Calorie Sweetened Beverages as a Replacement for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk: A Systematic Review and Meta-analysis.
JAMA Netw Open
PMID 32690176 • 2020 Aug
The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials.
Clin Nutr ESPEN
Open PubMedPMID 24881969 • 2014 Jul
Nutrition management guideline for maple syrup urine disease: an evidence- and consensus-based approach.
Mol Genet Metab
Open PubMedPMID 28954418 • 2017 Sep 26
Adherence to Mediterranean Diet and Risk of Cancer: An Updated Systematic Review and Meta-Analysis.
Nutrients
Open PubMedPMID 35987213 • 2022 Sep 1
Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance.
Cell
Open PubMedPMID 37673036 • 2023 Sep 5
Resistant starch decreases intrahepatic triglycerides in patients with NAFLD via gut microbiome alterations.
Cell Metab
Open PubMedPMID 39203835 • 2024 Aug 14
Efficacy of the Mediterranean Diet Containing Different Macronutrients on Non-Alcoholic Fatty Liver Disease.
Nutrients
Open PubMedPMID 30667502 • 2019 Jan 22
Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial.
JAMA
Open PubMedPMID 33684506 • 2021 Jul
Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial.
J Hepatol
Open PubMedPMID 38795741 • 2024 Jul
Curcumin supplementation alleviates hepatic fat content associated with modulation of gut microbiota-dependent bile acid metabolism in patients with nonalcoholic simple fatty liver disease: a randomized controlled trial.
Am J Clin Nutr
Open PubMedPMID 37552302 • 2023 Aug 8
Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Liver Cancer and Chronic Liver Disease Mortality.
JAMA
Open PubMedPMID 39342324 • 2024 Sep 28
Akkermansia muciniphila improve cognitive dysfunction by regulating BDNF and serotonin pathway in gut-liver-brain axis.
Microbiome
Open PubMedPMID 39102266 • 2024 Aug 1
Estimated Exposure to 6 Potentially Hepatotoxic Botanicals in US Adults.
JAMA Netw Open
Open PubMedPMID 19825397 • 2010 Jul
Coffee and liver diseases.
Fitoterapia
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=beef%20liver
Community Sources
PUBMED • 2021 • Human evidence curation set
PMID 34187442 from BMC Complement Med Ther.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35285920 from JAMA Netw Open.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32690176 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2014 • Human evidence curation set
PMID 24881969 from Mol Genet Metab.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28954418 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35987213 from Cell.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37673036 from Cell Metab.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39203835 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30667502 from JAMA.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33684506 from J Hepatol.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38795741 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37552302 from JAMA.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39342324 from Microbiome.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39102266 from JAMA Netw Open.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open sourcePUBMED • 2010 • Human evidence curation set
PMID 19825397 from Fitoterapia.
Outcome: See linked PubMed abstract for methods and outcomes.[1941,2313,2861, etc.]
Open source