Diet Protocol
Hybrid Mediterranean-DASH pattern emphasizing neuroprotective food groups.[2435,3332,3954, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
18
Positive Lean • confidence Moderate
Safety Friction
31/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 10 • links 25
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Best fit: Cognitive-aging risk reduction and long-term brain-health priorities..[429,1243,2435, etc.]
Goal alignment: Brain Health, Cognitive, Longevity.[429,1243,2435, etc.]
Protocol Type
Diet Plan
Evidence Tier
HIGH
Best Fit
Cognitive-aging risk reduction and long-term brain-health priorities.
Primary Focus
Brain Health, Cognitive
Clinical Depth
Humans: 213 • RCTs: 13 • Meta: 2
Cohort / Real-World
Cohort signals: 87
Safety Markers
Adverse signals: 4 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
↑ Growing evidence base
Depth
213 total studies · 3 recent
Timeline
Total indexed
213
Human studies
213
Adherence/dropout signals
132
Cohort signals
87
Randomized trials
13
Mechanistic signals
5
Weighted direction score: 18 (Positive Lean)
High when large human trial/meta/cohort volume exists for the named dietary protocol.
Total indexed
213
Human studies
213
Adherence/dropout signals
132
Cohort signals
87
Randomized trials
13
Mechanistic signals
5
Safety adverse signals
4
Meta-analyses
2
Distribution of evidence by study design strength
Evidence Strength: High
PMID 37105521 • 2023 Jul
Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and Cognitive Function and its Decline: A Prospective Study and Meta-analysis of Cohort Studies.
Am J Clin Nutr
Open PubMedPMID 37133875 • 2023 Jun 1
Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia.
JAMA Psychiatry
Open PubMedPMID 37466280 • 2023 Aug 17
Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons.
Benefit reports: 2
Adverse reports: 1
No-effect reports: 0
Mixed reports: 1
Unclear reports: 6
Signal confidence: 0.47
Benefits
Adverse
No Effect
Community confidence 0.47 with mentions: benefit 1, adverse 0, no-effect 0.
Subreddit coverage: ScientificNutrition, mediterraneandiet, nutrition.
post • r/nutrition • unclear
MIND Diet Tracking? If you are following the MIND Diet, what are you using to track your food? If you use an app, is it specific to MIND or are you using a generalized diet app? It seems there used to be some free apps out there but the on…
Open mentionpost • r/ScientificNutrition • unclear
Plasma Proteins Associated with the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet and Incident Dementia
Open mentionpost • r/mediterraneandiet • unclear
An almost perfect salad! Call me crazy, this is not your typical breakfast, but here we are, eating this colorful bowl at noon: mixed greens, quinoa, yellow bell pepper, cucumber, tomato, cannellini beans, strawberries, walnuts, olives, an…
Evidence Sources
PUBMED • Human diet protocol literature
Counts from structured PubMed protocol-specific query set.
Outcome: Humans 213, RCT 13, meta 2, cohort 87.[2435,3332,3954, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37105521 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[, etc.]
Composite of study volume, RCTs, and meta-analyses
N Engl J Med
PMID 40065021 • 2025 Mar 10
The effect of MIND diet on sleep status, mental health, and serum level of BDNF in overweight/obese diabetic women with insomnia: a randomized controlled trial.
Sci Rep
Open PubMedPMID 41058007 • 2025 Oct
Effect modifiers of the MIND diet for cognition in older adults: The MIND diet trial.
Alzheimers Dement
Open PubMedPMID 36117580 • 2022 Sep
The Effect of Short-term Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet on Hunger Hormones, Anthropometric Parameters, and Brain Structures in Middle-aged Overweight and Obese Women: A Randomized Controlled Trial.
Iran J Med Sci
Open PubMedPMID 35190536 • 2022 Feb 21
Effect of MIND diet intervention on cognitive performance and brain structure in healthy obese women: a randomized controlled trial.
Sci Rep
Open PubMedPMID 36429384 • 2022 Nov 8
Cardiac and Mental Benefits of Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet plus Forest Bathing (FB) versus MIND Diet among Older Chinese Adults: A Randomized Controlled Pilot Study.
Int J Environ Res Public Health
Open PubMedPMID 25681666 • 2015 Sep
MIND diet associated with reduced incidence of Alzheimer's disease.
Alzheimers Dement
Open PubMedPMID 31209456 • 2019 Nov 1
The Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diets Are Associated with Less Cognitive Decline and a Lower Risk of Alzheimer's Disease-A Review.
Adv Nutr
Open PubMedPMID 38776524 • 2024 Jun 11
Associations Between Ultra-Processed Food Consumption and Adverse Brain Health Outcomes.
Neurology
Open PubMedPMID 33989093 • 2022
MIND diet and cognitive performance in older adults: a systematic review.
Crit Rev Food Sci Nutr
Open PubMedPMID 36364826 • 2022 Oct 30
Diet in the Prevention of Alzheimer's Disease: Current Knowledge and Future Research Requirements.
Nutrients
Open PubMedPMID 33882663 • 2021
The role of nutrition in Alzheimer's disease.
Rocz Panstw Zakl Hig
Open PubMedPMID 33653258 • 2022
Alzheimer's Disease: Pathogenesis and Therapeutic Interventions.
Curr Aging Sci
Open PubMedPMID 36364733 • 2022 Oct 25
The Role of Diet and Dietary Patterns in Parkinson's Disease.
Nutrients
Open PubMedpost • r/mediterraneandiet • mixed
THIS should be the cornerstone of all weight loss programs The cornerstone of weight loss programs should be normalizing a high-fiber Mediterranean/DASH/MIND diet. Those who have been consuming a low-fiber diet and are gun shy about the si…
Open mentionpost • r/mediterraneandiet • benefit
University Project As the title of this post suggests, I am right now working on a project for my Nutrition class, and my topic is the MIND diet (Mediterranean-DASH Intervention for Neurodegenerative Delay), which, in basic words, is a hyb…
Open mentionpost • r/ScientificNutrition • unclear
Calorie/TDEE calculators: Why does a small change in calories equate to a large change in weight? I've calculated my daily calorie burn based on the TDEE calculator at [https://tdeecalculator.net/](https://tdeecalculator.net/) based on my …
Open mentioncomment • r/nutrition • unclear
I use FatSecret app. I've created my own diet and found out a few months ago that it's very close to the MIND diet.
Open mentioncomment • r/nutrition • unclear
The website i use most often if I log a day's food (which i don't do daily) is [myfooddata.com](http://myfooddata.com) (which is free and also has a free app i believe) It is not specific to the MIND diet; it let's you log any combination …
Open mentionCommunity Sources
PUBMED • 2023 • Human evidence curation set
PMID 37133875 from JAMA Psychiatry.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37466280 from N Engl J Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40065021 from Sci Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 41058007 from Alzheimers Dement.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36117580 from Iran J Med Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35190536 from Sci Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36429384 from Int J Environ Res Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25681666 from Alzheimers Dement.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31209456 from Adv Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38776524 from Neurology.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 33989093 from Crit Rev Food Sci Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36364826 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33882663 from Rocz Panstw Zakl Hig.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 33653258 from Curr Aging Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36364733 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[2435,3332,3954, etc.]
Open source